Question posted by RichardW on 25 June 2012
Last updated on 25 June 2012
I have just been prescribed delayed release Tramadol (Zydol) at 50mg every 12 hours for muscle pain (CFS/ME) and I already take 50mg Sumatriptan for migraines, only taken as needed not regularly.
Are these safe to take together?
I've just had 2 bouts of terrible terrible vomiting which could be illness could be more. Trying to get a GP appt in the meantime i've stopped taking the Tramadol, I can live with that pain I can't live with migraines.
Thanks
Richard,
Technically no, there is an interaction warning against the two. However, I take two meds they also have an interaction warning with the sumatriptan which I also take as needed for migraine. My dr is aware of this, but told me that since I'm not taking the two on a consistent basis together, there was little chance of a problem resulting. Notice I said little chance. I'm not saying that you should, just letting you know my doctor's thoughts on it. You should call his office and ask while you're making the appt. Like you, I'd give up any of my other meds to have the sumatriptin during a migraine! Hope this helps.
Lisa
Thanks Lisa. Really helpful I can live with muscle pain and almost any other pain but like you a migraine and that's it for me. I've had them since the age of 5 or so and it's only with the relatively recent release of the triptans I can actually lead a mostly normal life (i've actually lost a job over migraines in the past).
I think the illness was just that but I thought i'd err on the side of caution until I get an official ok from my GP.
Thanks again, hope your migraines aren't too bad
You're welcome Richard! Just a thought, have you tried the sumatriptin nasal spray? Neither the shots or the pills work for me, but the nasal spray works like a charm and it seems to be a bit quicker to work than some pills I've taken. As you know, where a migraine is concerned, the faster the better! Best of luck to you! :)
Lisa
The 2 together can cause serotonin syndrome. The extended release probably isn't as bad because its only 50 mg spread out. Did you get them at the same pharmacy? Did the pharmacist question it? Do you feel better after being off the tramadol for more then 24 hrs? I would hold the tramadol as you did, and see if I feel better. Truthfully I take 300mg of extended release a day and antidepressents without a problem, but that's me. The pharmacist would be the best place to get a good answer quickly.
I did feel better after stopping but hard to say whether it was a natural tummy bug running it's course. I don't normally react to other meds but there's no real telling I guess.
They came from the same Dr surgery and the prescriptions are filled by the surgery itself so I expect they should be ok and it's all a big coincidence as I don't normally get bad vomiting like that (migraine excepted) but I will double check just in case.
That's the thing with the practice fulfilling the scripts you don't see a pharmicist just a member of staff at the surgery. If I don't get an easy answer from the doctors i'll pop into a pharmacy in the week and ask there as you suggest.
Thanks for the reply
It is not recommended to be used together - Tramadol & Sumatriptan, you could read the details on this link: https://www.drugs.com/interactions-check.php?drug_list=2136-0,2221-0.
Best would be to talk to the doc/pharmacist who prescribed the meds. Take care.
Best wishes!
Yup that was my initial reaction but will have to wait to see that GP again probably be the best part of two weeks or so. I did see that link before posting but I wasn't sure how different the dosage works out with the 50mg prolonged release over a straight hit of 50mg.
Thanks for the reply
zydol, migraine, pain, fibromyalgia, muscle pain, chronic fatigue syndrome (cfs), sumatriptan, tramadol, muscle
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