Will Flexeril show up on a routine urine tox screen?
Question posted by o2cfc on 15 July 2010
Last updated on 24 October 2020
This question has also been asked and answered here: Will Flexeril (cyclobenzaprine) show up on a drug test?
I administer hundreds upon hundreds of drug tests on a monthly basis and never has an employer asked us to look for Flexeril aka cyclobenzaprine. If the medication is prescribed to you there is never a problem just bring your bottles to your UA testing. I have been doing this for 11 years and never have I had an employer care if your on any antidepressants or muscle relaxers!
I’ve worked in the medical field for 20+ years as a nurse, and just went to my doctor yesterday for an appointment. I am also prescribed Flexeril and had a urine test done. What do you know, I came back positive for tricyclics. As a nurse, I will tell you one thing: I do NOT take any scripts that are not mine, and I do NOT take any antidepressants. Flexeril is one of those medications that can make a UA come back “presumptive positive” for tricyclics, even though it is a not a tricyclic anti-depressant
So to answer your question, yes it can definitely come back on a tox screen as a tricyclic.
I’m sorry but all of you are misinformed. Flexeril is a muscle relaxant (cyclobenzaprine is the generic name). It is not a narcotic. However in some cases it will cause a FALSE positive for tricyclic antidepressants but in most cases will not. Most drug screens for employment or law agencies don’t test for antidepressants unless you are suppose to be taking them.
Lol, i guess this isn't the place to get answer's. Too many say yes, too many say no. Which one is it?
Just to educate not judge:
Flexeril (Cyclobenzaprine) belongs to the drug of class skeletal muscle relaxants.
Cyclobenzaprine – Can Cause False Positives For Tricyclic Antidepressants
I know it for a fact.
I just took Flexeril. I tested myself with 12 panel and came back positive for barbiturates
According to the Medscape app under flexeril and the pharmacology tab it states:
"Structurally related to cyclic antidepressants, and pharmacologic effects are similar, including reserpine antagonism, norepinephrine potentiation, potent peripheral and central anticholinergic effects, and sedation; reduces tonic somatic motor activity influencing alpha and gamma motor neurons"
This leads me to believe you could get a false positive for tricyclic antidepressants, which are potentially fatal if overdosed...
I was just prescribed flexeril for a pinched nerve in my back. I do weekly drug screens for my doctor. And antidepressants showed up in my test. After my urine was dent to a lab, it came back as my prescribed flexeril. So yes it does show up in a test. But its non-narcotic. It falls under category of antidepressants.
I work in a hospital lab as a MLS (medical laboratory scientist). You have to understand the testing before you can ask or answer this question.
First of all, there is qualitative (screen) tests and quantitative tests that not only give a positive or negative result, but an amount detected. The quantitative tests are the only ones usuable for legal cases such as court cases, probation, or pain clinic compliance.
The qualitative tests are mainly used in hospital ERs and in pre-employment drug screens. They are highly sensitive but not very specific, so false positives are common. They come in different kits that tests for different drugs. You may get lucky and not get tested for the drug you are abusing.
On the other end of the spectrum, quantitative testing basically tests for all drugs that can be abused, legal and illegal. First is a quantitative screen done on a clinical hospital style instrument via immunoassay. These tests are pretty sensitive and very specific. Once this tests positive, the lab will extract the drug and its metabolites from your urine via chemical means.
After the drug is extracted it will be analyzed via another means, usually gas chromatography. This method is close to infallible and will find even minute traces of the drug. Some labs even used a third testing method in the middlw of this process.
Long story short, if you are getting drug tested for a legal reason like court or pain clinic complaince good luck getting away with absusing drugs and passing your test unless you wait the correct amount of time for it to pass completely from your system.
Aldulturating your urine won't work either becuase they also test urine pH, specific gravity, creatinine, and other things affected by adulturation.
I just took a probation drug test and I had took 2 flexeril last night and today before before the test. It DID NOT show up ;-)
Both answers are correct. But also remember, there are spaces on the Ameritox form (one of several testing labs) where the tester can write in any medication the person paying for the test wants you tested for. There are also boxes they can check off (suboxone is one of them) if they want you tested for it. It all depends on how much money the test requester wants to pay and if they think you may be taking something other than the standard drugs they normally test for. Bottom line... most people do not want to pay for the more in depth testing. So I wouldn't worry at all.
MD toxicologist to the rescue.
Flexeril will not show up on a urine toxicology screen.
If this answer is helpful, please indicate such.
Flexaril is simply a muscle relaxent just like many people think soma is a narcotic because it has the potencial for addiction. NO it will not show up as anything on a UA(tox screen). Hope this was helpful have a good day!
- Flexeril uses and safety info
- Flexeril information for Healthcare Professionals (includes dosage details)
- Side effects of Flexeril (detailed)
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