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What is the different between diclofenac sodium and diclofenac potassium?

Responses (1)

robo 10 Aug 2009

Diclofenac is a non-steroidal anti-inflammatory drugs (NSAID) used to relieve pain and reduce inflammation.

Diclofenac exists in two forms - the sodium salt (diclofenac sodium) and the potassium salt (diclofenac potassium). Each has the same amount of diclofenac base - the main difference is that diclofenac potassium is slightly more soluble in water than diclofenac sodium.

Diclofenac potassium is generally considered to be more quickly absorbed and have a faster onset of analgesic activity than diclofenac sodium.

Diclofenac exists in the following branded products for oral use

Cambia 50 mg (diclofenac potassium for oral solution)
Cataflam 50 mg (diclofenac potassium immediate-release tablets)
Voltaren 75 mg (diclofenac sodium enteric-coated tablets)
Voltaren-XR 100 mg (diclofenac sodium extended-release tablets)
Zipsor 25 mg (diclofenac potassium) Liquid Filled Capsules

The different formulations of diclofenac cannot be considered equivalent even if the dose is the same.

shani123 14 Aug 2010

thz is difference thz is quality of both saltz

shani123 14 Aug 2010

thz is not difference thz is quality of both saltz

zainab729 29 Oct 2010

if the potassium salt form of diclofenac is more quickly absorbed:does this mean that less side effect of stomach uler and pain with respect to the soudium salt form?

tariq3 21 Nov 2010

no... because NSAIDS can effect stomach even they are given i.m so faster absorption does not rule out the chances of NSAIDS INDUCED ulcerS AND THEIR PAIN free discount card

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