I started taking Trintellix for about 2 weeks now, 5 mg first week and now taking 10mg, yesterday I started having horrible itching all over, has someone else had this and if so did it go away or is there something I can take to help? I would hate to stop taking it because it has really helped me through my depression and anxiety.
Vortioxetine - Trintellix and itching?
Question posted by Sgarciak on 6 Nov 2016
Last updated on 24 January 2020 by Budofhope
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6 Answers
Budofhope
25 Jan 2020
I have been on trintellix 5 mg and then 10 mg just up to 20 mg last week it changes started today there is no rash and I feel like I'm itching and crawling out of my skin, change sheets often and bought sensitive skin laundry pods
jennlk79
3 March 2019
I don’t remember if I was itching on 5mg, but I’ve been on 10mg for probably 6 months and I feel like the itching just keeps getting worse. It’s definitely not going away. It’s the most annoying thing and I can’t take it anymore. It is random places all over my body every 5 minutes or so. I’m changing to something else.
spiritscript
2 Sep 2018
HORRIBLE ITCHING!!! HIVES! BLEEDING!!! Doctors and pharmacists are CLUELESS!!!
Jimmie48
1 April 2017
I took Trintellix for a month. The first couple of weeks, my palms and soles of my feet itched like crazy. It didn't last long though. I just went off 3 or 4 days ago and now I itch all over!! I'm sure it will go away in a day or two, but it's extremely annoying right now. By the way, I tried taking Benadryl to help me sleep when I first starting taking Trintellix and it had the exact opposite effect on me. I couldn't sit still for more than an hour or two. It was horrible. Good luck!
jtarnow17
19 March 2018
how did you get the itching and rash to go away? No antihistamines worked for me. I stopped taking it but I took it for 3 weeks already.
Georgiabelle
6 Feb 2017
How long will I have uncontrolled itching talking 10 MG trintellix?
Sgarciak
6 Feb 2017
for me it lasted a few weeks, try taking an antihistamine it helped me.
gaynelle47
19 Nov 2016
I am having the same problem. I saw my doctor yesterday and mentioned the itching. He didn't seem concerned about it, but it is very annoying to me. The itching seems to move around to different parts of my body. Right now my little finger and my left foot are itching. If the itching doesn't go away, I will be forced to discontinue this medication. I have been taking it for about 2 weeks. The itching started when I went up to 10 mg. Please let me know if you have any more information about this problem.
Sgarciak
6 Feb 2017
I started taking zyrtec and it did help with the itching and after a 4 weeks the itching went away, I still will sometimes get it but very mild.
kipawaharder
1 April 2017
Oh boy, I am itching too! I am on my first week of 10 mg. after being on 5 mg. for 2 weeks. The itching started almost immediately - palms and soles of my feet. Now it is not so selective - chest, back, legs, you name it.
rabci
2 April 2017
I started 5 MG of trintellix 2 weeks ago while weaning off of paxil. I started the 10 MG a few days ago and I also have had itching. Started below my thumb and then yesterday and today my feet are driving me crazy, mostly just my left foot. I am also very Moody, happy one hour, then a bitch the next. I am hoping it is a lot to do with the medication change and that it will get better sooner rather than later. Nausea, lasted a couple hours the first few days and now only slightly. Keep praying for good lasting results.
giraffekass
14 Sep 2018
I started with 15mg which made me feel better in a few days. Then the itching started and the doc changed it to 10mg. 10mg wasn't helping after about 4 weeks so I went back to 15mg this week. Oh the darn itching, all over the place. I'm going to try to stick it out for a week or so and see what happens.
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pruritus, vortioxetine, trintellix
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