Oral antacids and some aluminum, calcium, and magnesium salts may decrease oral H2 blocker plasma concentrations. The mechanism may be related to reduced gastric absorption and bioavailability due to acid-neutralizing effects. Data vary and the clinical significance has not been clearly established. It is recommended that H2 blocker be administered one to two hours before one of these preparations.
However, for more info talk with a doc/pharmacist, please.
Take care, best wishes!
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