I started the medication three days ago after switching from Januvia due to kidney function. I have had higher than normal A1C levels (200 and above). My normal readings are 100 - 150. I do notice that after I exercise, my levels go down to as low as 130. Is exercise a requirement for this medication?
Linagliptin is a DPP-4 Inhibitor. These drugs work to block the enzyme responsible for the breakdown of a specific gut hormone that helps the body produce more insulin when blood glucose is high and reduces the amount of glucose produced by the liver. This inhibitor usually demonstrates its full effect in about a week. "It’s blocking that enzyme after the first dose a little bit, but by the time you get out to dose five, you’re blocking the majority of that enzyme,” (Sam Ellis, PharmD, BCPS, CDE, associate professor in the Department of Clinical Pharmacy at the University of Colorado)
- Tradjenta Information for Consumers
- Tradjenta Information for Healthcare Professionals (includes dosage details)
- Side Effects of Tradjenta (detailed)
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