My new pain management MD put me on Topamax for my daily headaches. I have tried MANY other drugs, notably Gabapentin helped some. I also have depression, but went off all my depression meds when I thought that they were contributing to my debilitating headaches. He rxed the Topamax at 25 mgm twice a day for a week, then 50 twice a day. About 45 minutes after the first dose, I became very nauseated. The next day, I was back in bed with severe depression. The next day, I cut the pill in 1/2 and took it with food, milk, Zofran, and Ginger Root. That combo helps some. Any further suggestions? My headaches have pretty much stopped for the past 4 days which is AWESOME, but the nausea is debilitating. Thanks in advance for your help!