I was told should not be?
Sharona; No you can take those two at the same time they do list a moderate interaction and that is because when you first start the Tizanidine can be more sedating so if you want to avoid it keep it an hour or two apart. hope this helps. And here is the copy and paste from drugs.com where I got this information. Interactions between your selected drugs
Applies to: tizanidine, Abilify (aripiprazole)
MONITOR: The sedative effect of tizanidine may be potentiated by concomitant use of other agents with central nervous system (CNS) depressant effects. In addition, tizanidine and many of these agents (e.g., alcohol, anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, muscle relaxants) also can exhibit hypotensive effects, which may be additive during coadministration and may increase the risk of symptomatic hypotension and orthostasis, particularly during initiation of therapy
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