Can I take Ambien with Percocet and tizanidine?

Taking these drugs together is not a good idea and could be dangerous because these drugs each work to relax the central nervous system which can cause the respiratory system to slow down. This means your breathing gets slow and shallow. Imagine your body needs air like a car needs fuel. This can happen when you take certain medicines, like strong painkillers or sleeping pills, especially if you take too much or mix them with other drugs.

Combining Ambien (zolpidem), Percocet (oxycodone and acetaminophen), and tizanidine can be potentially dangerous and should only be done under the strict supervision and guidance of a health care professional. All three of these medications can cause central nervous system depression, which can lead to serious side effects such as respiratory depression, coma, and even death.

Ambien is a sedative-hypnotic medication used to treat insomnia, while Percocet is a combination of oxycodone, an opioid pain reliever, and acetaminophen, a non-opioid pain reliever. Tizanidine is a muscle relaxant.

When combined, these drugs can potentiate each other's effects, increasing the risk of overdose and other adverse reactions.