Question posted by Nicoco777 on 17 Nov 2019
Last updated on 3 December 2019
I’ve been taking sertraline for about 2 months. First month 25mg and then 50mg. Second month 75mg and 100mg.
I’ve felt really better this last month: less depressed, less anxious, more energy, I was really happy with these results.
But last two days have been hard, I feel tired and not well.
I know a drug can stop working after a long time but that’s only a month !
Should I worry??
Thanks for your help !
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
You have to give the Zoloft time to build up in your blood stream, and the level in your brain, it's going to take longer than a month I'm afraid, when I was first started on Zoloft, and that was 12 years ago and I'm still taking it now, it took about a month and a half to get where I was feeling better, but it took longer than that to feel the full effect of it, and when I did it was like night became day, so give it a little time, and if it doesn't help, then talk to your doctor and let them know, I'm sure they'll try something else, it took a year and a half to finally get the right combination of meds when I was diagnosed with Bipolar 2, PTSD and some other psych issues, but I didn't give up, you shouldn't either, you'll get the right combination to, psych meds are about trial and error, the doc's have to try and put you on the right med, and that can take some time, hang in there, don't give up, and talk to your doc.
Thanks for your answer.
When Sertraline started to work for you, have you experimented bad days before it fully worked. Or when it worked did it work immediatly without any bad day?
Thanks for your kind help
I’m very sensitive to meds. I’ve only been able to stay on 25mg. It’s been 2 years now. Even that amount makes me tired. I tried increasing to 50mg after a few weeks & I felt worse. Many docs tend to keep increasing meds too quickly. For 90% of people 25mg isn’t even considered therapeutic. I’ve tried 4 other antidepressants that haven’t worked. Or was I told just to increase them because I felt worse??? Anyway, maybe ask your doc if going down in dose a bit may help? Just don’t believe that if you keep increasing you’ll feel better, with many people that’s not the answer.
Hi, Nicoco!
It would be highly unusual for an antidepressant to "poop out" after such a short period of time. You might want to ask your doctor about whether your current symptoms warrant another dosage increase... the maximum dosage is 200mg/day... or possibly a switch to a different medication.
The other possibility is that this is something else altogether... maybe you're coming down with something? Or have you more than usual stress in your life lately?
Either way I wouldn't worry too much. Just be sure to talk your doctor.
Best regards and I hope you're feeling better quickly.
Thanks for your answer WildcatVet.
There is nothing in my life that could justify what’s happening to me the last few days.
When I read the testimonials about sertraline I find nobody talking about a poop out after just a month.
My doctor says at the beginning of the treatment it’s possible to experiment that kind of event, that the body needs time to fully ajust the treatment. What do you think about that?
Thanks for your kind help
Last week was a bit better but this week is quite hard. I have seen my doctor and we have increased the dosage at 125mg Zoloft for about a week. For the moment days are very long and I feel desperate. I don’t understand why Zoloft worked for a month and stopped working without any reason :-(
Your metabolism probably adjusted to the original dosage but it wasn't enough to provide the full benefit of the medication. Dosage increases like this are common and should be effective within a couple weeks at most.
Good luck and I think you'll do fine.
Thanks for your answer WildcatVet!
I did not know it could happen to feel bad after Zoloft worked for a month.
My doctor doesn’t know how long it will take to work again with the new dosage. Maybe 2 weeks or can it be more like at the beginning of the treatment?
Thanks a lot for your help !
Two weeks might be long enough but I think it might take as long as four weeks. But hang in... you'll probably feel much better again.
WC
PS, BTW, You're more than welcome! That's what we're here for... to share our experiences with these medications and any information we may have learned in the process.
depression, anxiety, generalized anxiety disorder, sertraline, major depressive disorder
Still looking for answers? Try searching for what you seek or ask your own question.