Have used Bisacodyl 5 mg for constipation and wondering how it compares to sennosides 25 mg
Senna-Lax - What is the Difference in Sennosides and Bisacodyl?
Question posted by Jeffswife on 5 March 2011
Last updated on 10 June 2019 by Bradleybillingsley
Senna-Lax contains the active ingredient Sennosides which is a stimulant laxative. It works by irritating bowel tissues, resulting in bowel movements.
Bisacodyl is a laxative that stimulates bowel movements. It is used to treat constipation or to empty the bowels before surgery, colonoscopy, x-rays, or other intestinal medical procedure.
They both work to relieve constipation but their modes of action are slightly different.
I believe senna-lax is a little bit stronger.
My doctor, a Gastrointologist and my pharmist suggested to never use laxitives with senna or bisacodyl, they stain the inside of colon
For me, these two may be thought of as being essentially the same drug, but in two different strengths, as they both work via similar mechanisms but bisacodyl is considerably stronger — by a factor of 5× in my estimation.
I tend to see them the way I view two benzodiazepines : diazepam (Valium®) and alprazolam (Xanax®). Both those also work via the same mechanism of action more or less, but alprazolam is considerably stronger (in this case 10×) so the user can take 10mg diazepam or 1mg alprazolam and have similar effects. In this example there are in fact other differences to consider, such as each drug's half-life, but I'm referring only to strength.
Not everyone is the same of course, but let me say this... if someone who didn't know anything about this stuff were to ask me for a recommendation, I'd just straight up tell them to take 10mg bisacodyl, wouldn't really need to mention the senna.
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