I've had Major Depressive Disorder for the last 20yrs. 3yrs ago, I started seeing a psychiatrist & was put on Cymbalta. I got up to 60mg & I was feeling great! The problem was the side effects. Overnight I was incontinent while taking it. My body just would not wake me up so I could use the bathroom. Another side effect was that I was kicking & hitting whoever was around me during sleep. Anyone else experience this or something similar??