My doctor prescribed me Zoloft to help with my anxiety and and insomnia, however I wasn't given much of a guide for it. I took 1 pill last night but had a bad reaction, insomnia, aggression, irritation, thoughts of death, my anxiety spiked. They told me to stop taking it so I didn't take anymore however I have to be up at 4 am to work a 13 hour day shift at the hospital. I normally take melatonin but I am also currently sick with a cold and wanted to take melatonin to put me to sleep because that usually knocks me out. I'm scared that even though I took it 24 hours ago and it should have left my system by now I can still suffer from toxicity. Yes I am a nurse yes I should know this but I am also extremely worried about overdosing accidentally because I work in the psych department and see it a lot. I just want to be safe.
Hi, Vgutt! Since Zoloft has a long half life of approximately 26 hours, about 25mgs are still in your system. The use of any product containing dextromethorphan is contraindicated with SSRI class antidepressants so I would be very careful... serotonin syndrome is very rare but serious. Can you take your melatonin instead even though it won't help with your cold?
It would seem, also, that you are sensitive to these medications as the symptoms you described experiencing after taking your Zoloft, while common, mild, and to be expected, were exaggerated. You probably should have been started on the 25mg dose instead of 50mg.
Best regards and I hope you feel better soon! Wildcat
I. think you answered your own question as to take...
You side effects are darn rt scary. I.e aggression, irritation, thoughts of death?
What to try now?
Because you had what I call moderate-to-severe side effects I would consult your doctor before trying anything else.
Final idea, when you are awake and functioning despite your cold symptoms try to drink as many fluids as possible.
There's enough uncertainty here between the two drugs you definitely don't want to be dehydrated as well. I feel silly telling you this because I'm sure you knew to drink, drink & drink, esp with the cold.
- Zoloft Information for Consumers
- Zoloft Information for Healthcare Professionals (includes dosage details)
- Side Effects of Zoloft (detailed)
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Updated 30 Jan 2014 • 1 answer
Zoloft - On day 4 of my 25mg dose. Some effects not bad but mainly just insomnia. I am to up my dose
Updated 6 Jun 2014 • 1 answer
Updated 9 Jul 2016 • 1 answer
Updated 15 Jun 2017 • 1 answer
Updated 6 Nov 2018 • 2 answers