Hello chriswb! No, you should not split your dosage of Zoloft in half and take it in the morning and at night. In order for you to get the full effect of the drug, you should take it as prescribed. You may, however take the 50 mg in the morning or at bedtime. People who have sleeplessness as a side effect should take it in the morning. I also advice you not to change your meds in any way until you have consulted with your doctor. I wish you the best! Sweetie Pie
- Zoloft Information for Consumers
- Zoloft Information for Healthcare Professionals (includes dosage details)
- Side Effects of Zoloft (detailed)
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