takes 24 hours for antibiotic to start working but it could take several days to feel better. You didnt say why you were taking it, it is used alot for urinary tract infections and bladder infections. If this is the case you should drink as much water as you can and this will help also. If you do not feel better after 5 or 6 days i would call the dr. you might need a different antibiotic, not all actibiotics treat everything.
How long does it take bactrim D's to start working in your system?
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