I have started on this drug 9 days ago 200mg twice daily and as time goes on I am feeling more and more tired. I also have slight dizzyness but not bothersome. How long before side effects settle?
Is lethargy and tiredness a side effect of hydroxychloroquine?
Question posted by lesley66 on 21 June 2015
Last updated on 21 June 2015 by DrDonovan
There are countless numbers of reasons to have tiredness or fatigue so without knowing more about your history, reason for medication and other factors one can't comment if it's related or not.
In general, it's important to mention this to your prescriber. Hydroxychloroquine (Plaquenil and generics) can itself cause fatigue in some users, it can interrupt sleep patterns (especially by causing more vivid dreams) which in turn makes one more tired. The drug can also lower blood counts (red cell, white cells and others too) which in turn can cause fatigue. This is especially true in those individuals with G6PD deficiency.
All in all, it is important to discuss these side effects with your doctor in order yo determine if it is or is not related. Blood tests may be required for some patients with excessive tiredness and fatigue
- Hydroxychloroquine uses and safety info
- Hydroxychloroquine information for Healthcare Professionals (includes dosage details)
- Side effects of Hydroxychloroquine (detailed)
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