and side effects experienced by folks that have tried this? A compound pharmacy gave me 100mg to try, but I am always apprehensive about trying something new for fear of how my weirdo body reacts to things. I don't have official diagnosis but it seems like I have RSD. Could it help depression too? I've read there has been some success, but I don't know if nasal form would be the same.
Ketamine is an anesthetic that works by interrupting pathways in the brain to inhibit pain sensation. It can effect your cognition, causing confusion and hallucinations. It can interact with barbituates and narcotics. It reacts badly with amiodarone. I'm assuming your pharmacist considered any medications you are on before giving it to you. I found this on the spray specifically:
ketamine Nasal Spray
What Is It?: Ketamine, or ketamine hydrochloride, is a non-barbiturate, rapid-acting disassociative anesthetic used on both animals and humans. It may be compounded into topical/transdermal creams for the local treatment of pain. It may also be compounded into nasal sprays or drops for more generalized pain relief. Ketamine is only available by prescription.
How To Use: The compounded sprays and drops are usually ordered for the management of pain. Use as directed and only as frequently as prescribed. Additional use increases the risk of side effects and addiction. Do not increase your dose or stop abruptly without direct approval from your doctor.
Possible Side Effects and Warnings: While low doses of Ketamine can increase heart-rate, at higher doses it depresses consciousness and breathing and is extremely dangerous to combine with other depressant items like alcohol, Valium or GHB. Frequent, un-prescribed use can cause disruptions in consciousness and lead to neuroses or other mental disorders. Ketamine can cause psychological dependence (addiction.)
Storage: Keep in the original container. Keep out of the reach of children and pets. May be stored at room temperature. Some liquids should be stored in the refrigerator (see your prescription label.) Store all medicines away from excess heat and moisture. Do NOT store in the bathroom.
Note: Prescriptions for ketamine are not refillable. The pharmacy needs a new prescription for each order.
Hi my doctor recently prescribed me Ketamine Nasal Spray 60mg every other day to start to see how I respond. First dose was done in the office. It's compounded and the doctor was able to just call it in. I am also afraid to start/try new things as sometimes I will have the opposite reaction. Anyways, it's 10mg per spray which is 6 sprays per dose. I seemed to tolerate the initial dose ok while in the office. I felt really good for two hours, but then I started feeling miserable again, but it got better as the day went on. I kept taking it but honestly the week before I started using it was better. Every time I take it, the first two hours I feel good but then I feel worse. I was told what I would feel in the first two hours were side effects and the antidepressant effect could start later that day or in a few days. I am due for another dose tonight but I am not taking it for a few days to see how I do without it.
I am on other meds which my doctor is aware of except a new one Fioricet, which I take in the morning so I am not sure if this is interfering, or maybe the starting dose of 60mg is just too high for me. I may try it again at only 10mg to see and not take the Fioricet in the morning.
I was prescribed compound ketamine nasal spray 100mg/ml on 7/21/18 one spray every 4 hours. This was prescribed to me by a headache specialist on my first visit. I have had a migraine for 18 months. Tried everything available. I am also in pain management for my neck and back (opiates), tried all migraine rx’s, IV’s, Botox, occipital nerve blocks, etc etc... I started getting some relief pretty quick using this. One month later 8/21/18 went back to same dr. And was prescribed same except now I can have one spray per nostril (2) every 4 hours. I’m not cured of pain, but it definitely helps! side note... for my migraine... anew drug came out a couple of months ago and my first RX of it will be given to me the day after Labor Day. The specialist I saw was trained by the best at Diamond Clinic and told me none of my meds preventive and abortive would interfere with this medication. My experience- I would recommend it. Try it if it does not work for you stop. Best wishes for a pain free life for all of us!
kaismama: Great answer, thank you. One note to make though (and it just may have changed since you wrote that); ketamine nasal spray CAN be refilled without needing a new ‘script (at least in PA.) I get a paper script every few months and it’s good for 2 refills.
I had the ketamine infusion in my psychiatric Aprn's office, which is the only way you can be given ketamine by infusion aside from the nasal spray. However, because I don't have the time or even access to my doctor in person now in order to have infusions due to the pandemic, I thought the spray might be available by prescription but all I can find in PA are clinics that give it in their office. So, I'm surprised to read that some of your have been able to find doctors that allow you to take it at home. Does anyone know of a doctor in PA that allows for home use? I had it for TRD and then the pandemic hit so I was only given one treatment and then just left to wait...
- Ketamine Information for Consumers
- Ketamine Information for Healthcare Professionals (includes dosage details)
- Side Effects of Ketamine (detailed)
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