For quite some time I've been taking diphenhydramine (100-150mg) a night to fall asleep. Will this have an adverse effects on my health? Thank you!
Is diphenhydramine dangerous if taken nightly as a sleep aid?
Question posted by boyextraordinare on 7 Feb 2007
Last updated on 26 December 2018
14 Answers
I've been taking 75 milligrams of benadryl every single night for 20+ years and I've never had a problem. I haven't built up a tolerance, still take the same 3 pill dose. I fall asleep within 30 minutes after taking the pills, every night without fail. This stuff is a miracle drug.. Side note: if you have a tooth ache or mouth sore, just open up one of the benadryl pills and pour the powder on the painful area and it becomes completely numb..
I've been taking this for over 7 years as a sleep aid; for the last 3 nights I have been experiencing sleepless and extreme nausea and vomiting. It's OTC and the $1 brand. I'm staying up tonight to see if this is the cause. Please advise.
Please read all the previous posts and perhaps read some articles online as well.
This drug is definitely not something that is meant to be taken long term and especially not daily for any length of time. And it’s even more critical for people in their late 40-50’s. The data for dementia developing after long term, high dose use of this drug is growing rapidly.
Typical Americans. “I was told by doctors so it’s true”
People take doctors advices like they are God's.. When I hear someone say oh the doctor told me this and that I asked them.. If the doctor told you to lick the floor because it's full of Vitamins would you do it? Doctors are only human beings and aren't always right..
i take 87.5 mg every day .. basically 12.5 mg 7 times a day i have a disease causing my body 2 release histamine 24/7 so i must take a high daily dose of Diphenhydramine under drs care
if you take a huge dose at once it can make you " high" ppl have been known to hallucinate when abusing it. have u tried melatonin? it has less harsh side effects that daily dose of benadryl aka diphenhydramine has... make sure to ask ur dr if its safe im NOT a dr!!
I know this question is old but I had to say that I've been taking benadryl for 15 years everyday cuz I have allergies to everything and developed heart issues. So I suggest long term use not be used. I mentioned it to several Drs with no concerns until I found a smart Dr. Find the reasons like adrenal fatigue or thyroid issues.
I have used benadryl type sleep aids for about a decade, and do have severe adrenal fatigue. I'm 50 now. If the problem is caused by benadryl I'd be ecstatic! I'd like nothing better than my life back. I'd love to hear from others with Adrenal fatigue (M.E.) that have stopped benadryl; what you took for sleep aids instead, and if you were able to get your life back.
Also, links to scientific and medical articles discussing M.E. and Benadryl would be most gratefully accepted.
I have been taking Benadryl for 15 years for sleep aid and allergies. I want to stop but every time I do I feel ill after 3 days like I'm going through withdrawal. nausea, cold sweats trembling, so I give in and take the pills and it stops, its not in my head. I ask my doctor he said it was ok for me to take these for years. I'm afraid if I stop I'm gonna get sick like people who drink after they stop some actually die from it. what should I do?
I know this is 11 years late, but hopefully this could still be of use to someone.
Stopping diphenhydramine couldn't cause death the way stopping alcohol will -- there's no mechanism for that. I'd be more afraid of the longterm effects to memory/cognition. Still, if something builds a tolerance in your system, it can cause nonlethal withdrawal symptoms, so tapering off is probably a good idea to avoid the symptoms you've described. You can use the tapering period as a time to build up better sleep hygiene habits.
There are no safety recommendations for tapering this medication, so it's really going to depend on your own response on your sleep and mental state. You can try going down by small increments or larger ones. It might be easier with the liquid form for smaller increments, though, since the pill form is much easier to cut into halves or thirds.
Yes
Benadryl is an anticholinergic drug. These types of drugs cause dementia. I don't think this was well understood when the question was asked, so it's an important amendment. So for those of you finding this question on google, you need to talk to your doctor before taking this regularly.
I was told by my psychologist that I can take 150mg of diphenhydramine for sleep. I've been taking for the past few weeks, 75 mg instead, and it's worked. I suffer from PTSD and I've also got schitzoaffective disorder... which keeps me having lots of changing sleep patterns. Hard to function, let alone, to live. I take the ofc sleep meds, just diphenhydramine, not tylenol or any antihistamines added. Diphenhydramine does not mean, benadryl. That's just got it in there. Tylenol is in vicodin, but you don't call tylenol by itself, vicodin lol.
Minkusus, Benadryl is diphenhydramine. Diphenhydramine is also an antihistamine. Use google or the drugs.com site and you'll see. Benadryl is a brand of diphenhydramine.
As far as long term effects. Look up Benadryl or diphenhydramine and dementia on google then come back to me.
I am a 10 year 50mg daily user of diphenhydramine and am slowly stopping this stuff. The past few weeks I have been reducing to 1/2. Trust me, take this for long term and you increase risk of memory loss. It's widely known. And yes, I have terrible, and I mean terrible memory loss issues.
My mother has taken two Benadryl a night, for probably 30 years. She started losing her memory about three years ago. It is almost completely gone. She wears a diaper now.
People think that if you can buy something over the counter, that it is safe.
People are wrong.
My mother also took 2 Benadryl for about 10 years every night to help her sleep, and just like another poster said, she now has dementia so bad she has to wear diapers, can't take care of herself, hasn't talked for 3 years, she has the mind of a 2 year old. My dad and I were convinced it was the Benadryl and it was so freaky to just read on here that the exact same thing happened to their mom.
She has been diagnosed with Alzheimer's but she has never fit the normal patterns of someone with Alzheimer's. She is 68 years old and she has been "gone" from our lives for about 4 years.
Do not take Benadryl for extended periods of time... it can do great harm.
The person who commented that mother took for 30 yrs mother probably has dementia and doesnt have anything to do with this
@eurohorse: Correlation does not imply causation
Benadryl is diphenhydramine and that, only. It may have various dyes or inactive ingredients but yes, Benadryl’s only active ingredient is diphenhydramine.
I have been taking trazodone nightly for several years, at dosages my dr approves of course, and for me at least it’s been wonderful! No side effects that I can see (definitely not walking or driving in my sleep). I have anxiety and am an insomniac and a night owl. This puts me to sleep quickly, and once I’m asleep I don’t often wake up, even before I started it.
I guess it’s different for different people, but I definitely would and do recommend it based on my experiences. Of course if anyone goes on it and has any side effects they should talk to their dr. Maybe the medication should be stopped, but an adjustment in dosage could fix the problem too.
Depending on my stress level I take between 100-300 mg nightly. For many, 50 mg or even less is enough. I have a tendency to under-react to meds and for some types I need more. After I started taking it regularly (mid 50s) I told my drs I’d had an amazing revelation. If you sleep a steady amount of hours on a regular basis, you actually feel better! Told them I had literally never had that experience. I slept poorly from the very beginning.
First of all, diphenhydramine is not approved at single doses greater than 50 mg. Higher doses cause significant anticholinergic effects, including dry mouth, impaired sweating and heat dissipation, and most importantly, increases in blood pressure. 150 mg of diphenhydramine is without question an excessive dose.
Secondly, antihistamines interfere with normal sleep architecture, and are inappropriate choices for chronic sleep disorders. Trazodone would be a much safer option on a nightly basis than diphenhydramine, because it does not interfere with sleep quality. You may sleep with diphenhydramine, but the quality of your sleep is very likely to be poor if you use it chronically.
See your doctor.
I've taken diphenhydramine 75mg and was told by my doctor that I can take 150mg safely. Just don't exceed 400mg in a 24 hour period. At 75 it puts me out, and the only side effect is a little cold sensation in my feet or my leg. As for trazodone, I had a terrible side effect. It gave me an erecting for about 5 hours!! Very painful, bleeding and I was totally embarrassed having to go to the er like that. I would never recommend trazodone.
Trazodone is NOT safer! I was on it for a week and kept waking up with weird bruises then found out I'd been leaving my house and DRIVING! Without any memory or knowledge of it. Not even dreams. I went to bed and woke up in bed then found out I'd been leaving my house all night. Absolutely terrifying! No prior history of sleep walking or anything related before or after that week, and I haven't had a dream since.
Taking trazadone is a bad mistake due to the nature of benzo drugs. Don't use them any more than one time because they damage the nervous system causing severe receptor rebound. It can take up to a year to recover from a rebound! Benadryl isn't harmful like this but any sedating medication can be abused! It's much safer than any benzo drug for sleep, sedation, relaxation. Nothing will help as much as meditation and relaxing the stresses in ones life.
I had a horrible experience with Trazadone. I would wake up in a short while with an extremely elevated heart rate.
Did your doc tell you that Trazadone was safer??? I took that for one night, and when my doc prescribed it he told me that I can only take it for a short time. He also told me to take it one SECOND before I'm ready to lie down. Well I didn't, I was still standing, took the pill, and I had a weird "out of body" feeling. Like I was disconnected from my body. I would stick with Benadryl.
I have been an insomniac for 8 years this August- I remember because it was the beginning of it when my little sweetheart son was born. I took OTC for years, with very little breaks in between Maybe for 3 years, then I was fine then back on for a few years etc... yep= taking every night. I tried Herbal remedies such as valerian, chamomile, hops and passionflower which seemed to help a bit. I am now on Imovane (zopiclone).
I
Please dont take this as a green light, but just my experience. I havent had any side effects of yet, but I know I was abusing them so would be surpirsed if some come up. I have treid everything. Some things worked okay (3-4 hours of sleep) like the herbs.
My insomnia is anxiety/depression based based due to childhood trauma, but am not willing to wokr through that muck yet.
Good luck to you
I too had unresolved issues that bubbled up when my son was born. I completely understand not wanting to work through the "muck" yet. I was experiencing more than insomnia in regards to my health, so I did go into therapy. After a while I realized having my son gave me the courage to do it. I'm not saying it was easy, it was brutal at times. I just had to remind myself it was over and I had survived. No one can tell you when it's YOUR time to seek therapy. You survived the trauma. Therapy and emotional health is a gift you give yourself and that little girl inside you...
You should not use OTC sleep aids for long term therapy - it is only indicated for short term use - Normally recommended for less than 2 weeks and the only 3 days at a time. A consultation with a Pharmacist or Doctor may help you figure out what the root cause of your sleep problems are. You may (likely) also have rebound insomnia after prolonged use of OTC sleep aids.
I was told to just take a benadryl at night since it was cheaper than buying the sleeping pill versions.
I was told it was the best type of sleeping pill to take as it is helpful to your system, non addictive and if you have allergies it will help with that too.
Diphenhydramine, better known as benadryl is commonly prescribed in skilled nursing facilities as a sleep aid. It's a medication that is primarily used to treat allergies, and does not contain any addictive forms of Scheduled medications that are controlled, like ambien or any of the other medications for sleep aid that are prescribed. Most commonly, doctors will prescribe 50 mg of Diphenhydramine at HS (hours of sleep) or bedtime if needed by a patient. They are used due to the drowsing effect of the medication, and will also cure that night time sniffle runny nose some of us get.
If nothing else, you'll be allergy free and have a great nights sleep. If it works, use it, but also too, contact your doctor and make sure it's okay for you to take on a regular basis. Many times in forums such as this people look to get answers, but don't take advantage of the one they should be looking to. However i'm sure he'd much rather you do the benadryl route as a sleep aid than the ambien route. Also too, do some research on what not to do so many hours before sleep. Too many people complain that they can't get a good nights sleep but drink a quadruple shot of mochachino or the 44 oz bladder buster soda an hour before bedtime and wonder why they're restless in bed. Do some research, a great nights sleep will be your reward.
Cowboy.
Related topics
Further information
- Diphenhydramine uses and safety info
- Diphenhydramine prescribing info & package insert (for Health Professionals)
- Side effects of Diphenhydramine (detailed)
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