Interactions between your selected drugs
atenolol ↔ bupropion
Applies to: atenolol, bupropion
MONITOR: Many psychotherapeutic and CNS-active agents (e.g., anxiolytics, sedatives, hypnotics, antidepressants, antipsychotics, opioids, alcohol, muscle relaxants) exhibit hypotensive effects, especially during initiation of therapy and dose escalation. Coadministration with antihypertensive agents, in particular vasodilators and alpha-blockers, may result in additive effects on blood pressure and orthostasis.
MANAGEMENT: Caution is advised during coadministration of these agents. Close monitoring for development of hypotension is recommended. Patients should be advised to avoid rising abruptly from a sitting or recumbent position and to notify their physician if they experience dizziness, lightheadedness, syncope, orthostasis, or tachycardia.
Other drugs that your selected drugs interact with
atenolol interacts with more than 300 other drugs.
bupropion interacts with more than 300 other drugs.
Interactions between your selected drugs and food
atenolol ↔ food
Applies to: atenolol
GENERALLY AVOID: Orange juice may moderately reduce the bioavailability of atenolol by interfering with its absorption from the gastrointestinal tract. In a pharmacokinetic study, subjects ingested 200 mL orange juice 3 times daily for 3 days and twice daily on the fourth day, and took 50 mg atenolol with 200 mL orange juice on day 3. The average peak plasma concentration (Cmax) of atenolol fell by 49% and the area under the concentration-time curve (AUC) fell by 40% in comparison to subjects who drank only water. In addition, the presence of food may reduce the bioavailability of atenolol by 20%. The clinical significance is unknown.
MANAGEMENT: Patients treated orally with atenolol should be advised to take atenolol at the same time each day and to avoid consumption of large amounts of orange juice to prevent any undue fluctuations in serum drug levels. Monitoring for altered efficacy of atenolol may be advisable.
Yes, but your blood pressure needs to be monitored in the beginning while you are adjusting to the doseage and anytime the dosages are changed. You can have a hypotensive response which is low blood pressure in case you didn't know.
Just thought I would reiterate what Maso said. Hope this helps,
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 20 May 2011 • 1 answer
I currently take the following medications for high blood pressure. Perindoprol 2mg, Atenolol 50mg &
Posted 6 Aug 2011 • 1 answer
High Blood Pressure - I have been taking Atenolol for about 9 years, changing dosage at times due to
Posted 1 Apr 2013 • 2 answers
Posted 2 Apr 2013 • 1 answer
Posted 13 Feb 2014 • 1 answer