... supplements, but no noticable problem with food containing Tryptophan. I take quite alot of protein shakes(bodybuilding) and my protein powder contains Tryptophan. Its a whey protein, and I would assume comes from natural substances. Every proetin that I read about, seems to contain Tryptophan!!! Do I really have to stop taking protein powder!!!
Can I take Citalopram with supplements containing Tryptophan.
Question posted by jbellx3 on 31 Aug 2009
Last updated on 10 September 2009 by suzanne66
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Answers
This is from the drugs.com interaction checker for Citalopram and Tryptophan:
citalopram and tryptophan (Major Drug-Drug)
GENERALLY AVOID: Concomitant use of agents with serotonergic activity such as serotonin reuptake inhibitors and tryptophan may potentiate the risk of serotonin syndrome, which is a rare but serious and potentially fatal condition thought to result from hyperstimulation of brainstem 5-HT1A and 2A receptors. Symptoms of the serotonin syndrome may include mental status changes such as irritability, altered consciousness, confusion, hallucinations, and coma; autonomic dysfunction such as tachycardia, hyperthermia, diaphoresis, shivering, blood pressure lability, and mydriasis; neuromuscular abnormalities such as hyperreflexia, myoclonus, tremor, rigidity, and ataxia; and gastrointestinal symptoms such as abdominal cramping, nausea, vomiting, and diarrhea.
MANAGEMENT: The concomitant use of serotonin reuptake inhibitors and tryptophan should be avoided.
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