I took .5 mg of xanax (alprazolam) for the first time in probably 6 to 9 months. One time only every few months but i wanted to know how long it would be in my system consider i have to take a drug test in about 2 weeks. I am about 5'4 130 pounds. Please help with any information!!
There is no exact number for the time it takes for a drug to be completely eliminated from the body. Drug metabolism is affected by many variables - age, smoking status, other drugs, liver function, kidney function etc.
Most drugs have what is called an "elimination half life" which is the time it takes for the drug to reach half of its pharmacologic activity. For Xanax this is about 11.2 hours.
The mean plasma elimination half-life of Xanax is reported to be 11.2 hours. The full range is from 6.3 to 26.9 hours in healthy adults.
For a drug to be totally eliminated from your system it takes 5.5 times the half life.
If we take the maximum time of 26.9 hours times 5.5, it will be in your system for approximately 148 hours i.e. 6 days, after your final dose.
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