... going off it? I haven't been able to find this information anywhere. The doctor took my mother off this drug, which is very good, but we don't know how long it will stay in her system. The drug has made her confusion a hundred times worse. Plus it hass made her argumentative, paranoid, and aggressive, etc.
How long does it typically take for Namenda to work its way completely out of your system after?
Question posted by jgreg1957 on 26 Dec 2011
Last updated on 30 October 2012 by Anonymous
Jgreg1957, welcome to the site. I do hope by now our mother is doing better. New studies have showed that Nemda does not help in conjuction with Aricept for helping cognitive behaviors. As far as how long it takes to leave your system read the following or check with her pharmacist if you do not understandd this:
Terminal half-life is approximately 60–80 hours.1
In patients with hepatic impairment, only a modest effect on clearance is expected.1
Renal impairment increases exposure.1 AUC increased by 4, 60, or 115% in individuals with mild (Clcr >50 but <80 mL/minute), moderate (Clcr 30–49 mL/minute), or severe (Clcr 5–29 mL/minute) renal impairment, respectively.1 Terminal elimination half-life increased by 18, 41, or 95% in those with mild, moderate, or severe renal impairment, respectively.1 (See Renal Impairment under Dosage and Administration and under Cautions.)
In geriatric patients, pharmacokinetics similar to those in younger adults.
Wishing you both the best...
- Namenda uses and safety info
- Namenda information for Healthcare Professionals (includes dosage details)
- Side effects of Namenda (detailed)
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