i have heard that Antibiotics such as Metronidazole ( flagyl ) has bad effects on liver ... but if effects are there and liver is not working properly ..and if its not producing digestive enzymes properly then what is the remedy to this problem?
How does metronidazole (flagyl) affects the liver performance?& if it does then what is the remedy?
Question posted by mrfuad2007 on 14 Feb 2011
Last updated on 14 February 2011
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Answers
After reading the monograph for flagyl, I found nothing suggesting that it adversely affects the liver. If your liver is not working properly your doseage of flagyl may have to be decreased. Is your doctor aware of the problem with your liver? What I found in relation to the liver is as follows:
Patients with severe hepatic impairment metabolize metronidazole more slowly, and increased concentrations of the drug and metabolites may occur.
Use with caution, monitor plasma metronidazole concentrations, and reduce dosage in patients with severe hepatic impairment.
Hope this clears up your concern,
Laurie
Thanks laurie, ...
well i'm not taking metronidazole now a days ... but in past i have taken much ... thats why i feel that may be some problem is there with my liver function.. but Tests are clear ... LFT is normal ... but it was just i heard from people ... May i misunderstood my problem.
in fact i am suffering from IBS, Thats what the doctor says... what i am looking is the cure to this problem ... Metronidazole helps in some way but if it adverse affects the liver then i should change my medication.
but if its nothing wrong to take 2 tablets of 400mg in a day and two days in a weak, and if it doesn't cause problem to become worst and if it doesn't make me habitual for this ... then i can continue with this. is it fine to take it in this way for the whole life? because i feel Doctors don't have cure to IBS they just suggest diet plan & partial treatments.
Hey mrfaud,
Not sure that metronidazole is the answer to the IBS problem. It is an antibiotic for bacterial and amoebic infections. Has a doctor recommended that you take it twice a week? This is called prophylactic use of the antibiotic and must be prescribed by your doctor. You run the risk of developing bacteria that are resistant to the drug and then will have a harder time curing if you ever do have an infection.
I do not recommend you take the metronidazole on an on going basis unless you are under a doctor's care.
Laurie
Thanks a lot Laurie ... Yes you are right ..for such kind of treatment it should be avoided.. no doctor has not suggested me to take medicine in such interval... its self medication which should be avoided..
Actually i usually avoid the medications .. i use to prefer the treatment through diet ... but i tell when it comes up more disturbance in stomach .. i have to take the metronidazole.. i don't know but it really feels better after taking it...
Well thanks for that .. it really helped me..
Not positive on this but I do know you can purchase digestive enzymes from health food stores like GNC. I got some because I have to take alot of prilosec and was worried about my food not digesting because the prilosec shuts down the acid pumps. Pharmacist might be able to explain this to you and get you a different remedy. Do NOT drink on the metro, you will hurl violently if you do.
Thanks matthi , actually i am really careful about my diet already... but still i feel that just taking metronidazole or such medication which only helps in digestion is not the solution to problem... what i am looking for the cure to the problem. This time i am suffering from IBS.
this was back in 1975 (I think) I was on Flagyl and the G.I. doctor gave me some digestive enzymes if I remember correctly they were called Ku-zyme capsule I took something like 2capsules with each meal, that may even be able to be purchased (or similar to that over the counter wow thats been a long time) I hope you do well
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flagyl, metronidazole, antibiotics
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