I have been searching site after site looking for the answer on how to maximize Suboxone absorption and still all I have found is "tricks" and products that do not make a difference. I want to post this question and answer this question myself because I have finally found an answer. From an actual neurologist!! (I hope I spelled that correctly)
How do I maximize Sboxone absorption?
- Asked
- 13 Dec 2009 by sarrocks1
- Updated
- 10 February 2019 (8 days ago)
- Topics
- suboxone, opiate dependence
Responses (23)
AFTER MONTHS OF SEARCHING FOR THE ANSWER AND GETTING NOTHING BUT OPINIONS FROM OTHER USERS, I HAVE SPOKE TO AN ACTUAL NEUROLOGIST ABOUT THIS AND HERE IS WHAT HIS ANSWER WAS:
"No matter what, 2 different people will take suboxone the same way and normally get 2 different results. So it is different for everyone. If one person says "hey, I took mine with excedrin and it worked so much better", this might be true for him, but for you, it might be a waste of time. What I can tell you is this: Put it under your tongue, wait for that potent taste to turn completely bitter (about 30min per 8mg), then SWALLOW. There are some people who swear that swallowing the Suboxone activates the Naloxone and makes you sick... blah blah... If you are one of these people, then spit. But swallowing the Suboxone will not make any difference. Besides, there are some <=1% buprenorphine left over after you dissolve for that long anyway.
Thanks so much for going thru the trouble of asking the question, finding the answer, and posting it. I knew that letting it dissolve as slow as possible seemed to work for me, but didn't know that it should take 30 minutes.I have also observed that, for me, it seems that it takes a full 2 hours for it to completely hit my system. I am continually disappointed that people who are prescribed suboxone are given very little information about all the little ins and outs of the drug. I was told it was non-addictive, apparently that is not true. I actually was told that it could cause sensory illusions and so many people aren't told that. I experience that effect full force the second day and luckily for me, I was attending a group counseling session with at least 12 other people who had been on it for longer than I had.
Anonymous,
I know that your post was 9 years ago, but I quickly wanted to post and agree with you. Doctors are told what to believe by Reps, and Reps are there for one reason, to sell belief in the drug to the doctors, and in turn achieve more sales, PERIOD! I doubt that even 1 out of 100 pharm. Reps truly care about the patients receiving the medicine. It's a sad situation, and not because of the Reps, they are just doing their job, but because the doctors aren't doing their own research and in the end it's just all about the more green.
In my opinion, dissolve under your tongue for around 30 min, if your mouth is dry it's twice as long. If you feel a burning sensation on your tounge that's the golden ticket, that's how you wanna do it. Pills can be a pain, I suggest pressing your tounge on the pill that won't hurt it. I personally, hold my tounge right on the gum line or right on it with pills and strips it will dissolve into your tounge for sure that way. Hope this helps someone, also the wait 24 hours after opioids isn't always true. If you have withdrawal symptoms, your good to take it.
I agree, thank you for the post. I am a suboxone user and an ex-opiare abuser and have tried every way to get the most out of my suboxone and this is what works best for me. I think it is sometimes hard because I feel sick if it is too early in the morning and it seems to upset my stomach when it seems to take so so long to dissolve but when I dont take it the right length of time, it seems to make me get a tummy ache and most times I will puke and I gag from the taste of the Suboxone. I appreciate the help and acvice and also I thank mVPT who has helped me to feel better by taking the lesser dose and it works better for my body. I was taking 12mgs and weigh 130..I went down to 10mg, and the little amount made a huge difference, Does anyone ever skip there sub for a day?
Actually, I have skipped a full dose one day, actually, here and there I will skip a day so that they day after I skip the dose, I can FULLY enjoy sex with my girlfriend. I know alot of you all fell this way as well but when taking Suboxone regularly, my libido is significantly decreased... The only way I can really enjoy sex these days is to skip a full day. Which for me and most other Suboxone users, does not make any difference. Remember, Buprenorphine has a ~37 hour half life. From my own experience, I have gotten away from taking it for 2 days in a row without any significant withdrawl symptoms. Also, I take a high dose so I usually have NIGHTMARES EVERY NIGHT and OIC (opiod-induced constipation) which for me, can be helped by either skipping a dose or significantly lowering the dose temporarily. It's not easy remaining 100% comfortable while taking Suboxone but I do find ways to keep myself happy. I am glad you all like my post as it does hold alot of truth.
I have a side effect from Suboxone, that my doctor swears cannot be from the medicine. When I take it I sweat profusely. I am positive it is from bupes. This happens to my friend also. But, any discomfort or slight uncomfortable feeling is completely outweighed by the benefits of the medicine. I don't have the constant obsession going on in my brain, I am not withdrawing, I don't have the people, places, things, and chaos that goes with active heroin addiction, and I am not on methadone. With methadone I got high, so it just continued my addiction. I don't mind the taste, I don't mind waiting for it to kick in, I don't mind putting it under my tongue, I've done much worse with heroin. For me it is a miracle pill, and a little bit of sweat(and taking forever to pee) is okay with me. I am able to lead a full and productive life.
I have been on suboxone 8mg tablets for two years now. I don't like the strips at all. Anyways I agree that for each individual the answer will vary. I personally cant stand the taste and the method I use is I use a pill crusher to crush my pill , then I pour the whole crushed tab under my tongue and then I take a sip of warm/hot coffee and leave it under my tongue for 20 minutes and spit it out. This almost completely eliminates the taste so I can actually leave it in until it hurts to hold my mouth like that. Every other way ive ever tried doesn't work as well because the taste in my mouth makes me gag and sometimes even vomit... so the pill dissolves almost instantly and the taste is masked by sugary coffee. win.
hi melissa82. R/B Pharmaceuticals even states in there doctors version of their literature on Suboxone that the taste of Suboxone was put in there just to make people NOT LIKE THE TASTE. By doing this it keeps addicts from enjoying the ritual of taking this medication. Studies have been done on what makes addicts go back to doing drugs and it seems that whole process or ritual is very hard to break. From getting money all the way to having the right equipment is all the rituals an addict has to break to fully recover.
I still fully feel like an addict using suboxone. I feel like I can't believe doctors think this is better for me than opiates and that I can legally take this stuff and still pass any drug test for work cuz its prescribed. I feel like one day the doctors are gonna catch on that people actually enjoy the "high" from suboxone and most people on suboxone are still true drug addicts, it's just now a drug that is "ok" to take cuz a dr prescribes it. Which is the same way most people started on opiates in the first place,,, PRESCRIBED BY THEIR DOCTOR SO WE THOUGHT IT WAS OK, it's a viscous cycle
hi family,when i first found out about suboxone or subutex,the doctor who tought me the best way to achive max absorbtion is this: drinking hot liquid and holding it under my tongue.then dry out under it with a napkin.put the crushed up pill under tongue,lean foward so no syliva get swollowed,paint the inside of your mouth with your tongue. all this should take about 20-to 30 min. spitting or swollowing depends on if you get headaches,if you do spit if you dont swollow.the longer you hold it in your mouth the better the absorbtion.the only better way I have tryed is by mixing a little baking soda with the hot water it opens up all the pours in your mouth,but we dont always have the time to do all this,but the diffrence is that you can find the least amount of sub that will hold you for the longest time... pete
Thanks for the information! Always wondered what the most effective method was.
So you did all this research and asked a BRAIN DOCTOR who wouldn't know any more about sublingual drug absorption than any other doctor and you found out that FOLLOWING THE INSTRUCTIONS ON THE BOX is the best way to take it... are you serious
LOL, funny comment, but yeah ANY doctor will be very familiar with methods of absorption and entry into the human body by any means. They study that in basic physiology during med school. But funny as hell, yeah, all that research just to follow directions on the box! I found some great ways to maximize absorption. I can always tell the difference when I take the time to do it, but posted it up there in a reply.
Well since medicine/drugs affect the brain when ingesting them then yes, you'd definitely want to ask a neurologist.
Intrarectal buprenorphine has a >50% bioavailability. Of course, the naloxone has a greater absorption rate as well. It's >15% when taken intrarectal.
Just boof it.
I put the pill under my tongue a1/4 at a time throughout the day..usually only feel great 3to 4 days a week. ..yes I have trouble peeing and, sex is less. .no libido...
Can't drink w out getting sick... and gives terrible hangovers. . So I almost stopped drinking... I still feel guilty for taking this drug... and get wierd thoughts sometimes. ... I wished I had all the answers, I wished I could stop talking it, ,but I'm afraid of detox,,and never feeling good. ... but put it under tongue take a drink of coffee,,and suckle it till dissolved... that's all. ..now how do I get myself to feel less guilty and is there a better way too take it?
O how I wish I had the courage to get off of these.
There is a way but try with half of what you normally take because this will increase absorption 3 fold. Any that dissolves will eventually find its way into your stomach and its bioavailability is very low. Place half under your tongue just before falling asleep for 4 or more hours. This decreases saliva and allows you to absorb far more then when tested by scientists. Even after 8 hours of sleeping I can taste it when waking. You can immediately tell your dose was increased while saving half.
I started taking this as soon as it came out. The doctor told me that it HAS to get absorbed through the veins on the bottom of the tongue. Anything swallowed will get pooped out and not have any affect whatsoever. So ignore the baloney about painting your mouth with your tongue and ignore the one about sleeping with it in your mouth. It will NOT stay positioned under your tongue when you're sleeping. I have found that you need to hold it down hard with your tongue and don't let a lot of saliva in there with it. For as long as possible. I got on here to receive advice only to feel obligated to let people know this.
Mine sometimes takes more than 30min and usually ends by me talking or swallowing what's left. Been taking it 10yrs so usually the only difference it makes to me is if I work late I start feeling more wore down if my dissolve time gets interrupted.
I've really never had a problem with absorption of sub even if I take 1 MG it does me just fine let it set for 5 or so min then drink a mt dew and that's that last 24+ hours I been on sub for 5+ years started on 16 MG and have been down to .5 and back and forth but always the same method 5 min then wash down with mt Dew
How do I get the response to her question? Please answer. Thank you

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dear, you r 100 % correct. maybe im lucky,as some nites i forget to pt 3--- 8mgs under tonuge,as im quite disabled at 57,n damit,i kicked opiods,heavy 10 yr useage,n now im bitten by zanax... three 1mg daily although i want a 4 th.told my medical psych,im ready to get off,n she warned me... its a bitch,but soon ill try.god bless
Just thought I,d throw in my drs. instructions. Sit down, place under tongue, close mouth, tilt head forward if you want. Sit there quietly for 5 mins. After that spit or swallow then don,t eat, drink or smoke for another 5 mins.
Thank you for posting this, I'm looking for the right way to take it to and there are so many different opinions.
Thanks for the info! It takes me forever I thought till I did some reading on it. I didn't know you weren't allowed to swallow till it was completely desollved. I take 2 doses separately, 6 × 2mg tables at a time. And I sit there for almost an hour most days! I'll try taking one 8mg tablet at a time tomorrow, and not swallow during the desollving process. But that sure is a long time to hold in all that saliva haha..
:) thanks again!!
Seems right,logical.Your letting it absorb slowly,not swallowing saliva into stomach which defeats purpose of absorbing through membranes of mouth.Hey,just thought of that song-insane in the membrane,going insane,got no brain!
Neurontin also works
R U saying that you wait 30min for 8 mg to dissolve? I'm trying to understand.
I seem to feel as though putting rough side up under my tongue doesn't leave a bad taste but that's me and being on this for years. I never spit but I do swallow with a drink.
I know this post is old but I stumbled upon it today so maybe my comment will help someone else. Honest, I will put it under tongue and hold it at least 20 min, I know it sounds long but I keep myself busy and as I go to swallow I sip a coffee behind it. Not a full gulp, and if need be I sip another. Coffee immediately takes the taste away. I wold wait to smoke for sure. Smoking, from what I understand will tighten up veins in your mouth and because the suboxone is absorbed in the veins under your tongue it can't be good to smoke soon after taking it. I am not a professional but I have been taking subs this way for 7 years.
This is for jolter, your Dr gave you bad info, you need to keep it in your mouth for a minimum of 20 minutes. I have found though it sounds disgusting, after 20 minutes I spit into an old med bottle, after 3 doses, I get a good 4th one by reusing the spit for another 20 minutes, I refrigerate it of course. There is still a lot of buprenorphine left after 20 minutes, not 1%, more like 30 to 40%
You say this was a neurologist ? Called you stupid last word in there was stupid wow ! How professional even though it did make sense very rude to talk to you that way.
Now in previous it said per neurologist 30 minutes I dont think anyone has had just one amount of time to leave it there and omg the little white ones in foil are the nastiest tasting thing I have ever had
Ok I can go for what your saying as that's how I administer my medicine as well, but what if it's the strips not the pills? Would it still work the same OR BETTER if instead of putting under the tongue if u took it in your cheek(buccal)
?? I'm only asking because my dose doesn't last me like it use to too, I've been on 2.5 I'm gonna strips for about 11months now give or take... I have been starting to get that feeling within my legs and just that yucky feeling in my body period towards the evening time and would just like to know if it made ANY longterm difference if I took it that way instead?! T.I.A