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I have angle glaucoma can I take amitriptyline?

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Answers

masso 13 March 2025


Amitriptyline Disease Interactions
There are 20 disease interactions with amitriptyline.

Anticholinergic effects
Cardiovascular disease
Pheochromocytoma
Acute myocardial infarction recovery
Cardiovascular disease
Seizure disorders
Bone marrow suppression
Diabetes
Renal/liver disease
Schizophrenia/bipolar disorder
Tardive dyskinesia
Acute alcohol intoxication
Bipolar disorder screening
Glaucoma
Hyper/hypoglycemia
Liver/renal disease
Neutropenia
Schizophrenia
Thyroid disorders
Urinary retention

Glaucoma
There is a moderate drug-disease interaction, moderate meaning;

Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.

Moderate
Tricyclic antidepressants (applies to amitriptyline) glaucoma
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Glaucoma (Narrow Angle)

Tricyclic antidepressants as other type of antidepressants have an effect on pupil size causing dilation. This effect can potentially narrow the eye angle resulting in increased intraocular pressure and angle closure glaucoma, especially in predisposed patients. These drugs should be used with caution in patients with anatomically narrow angle or history of glaucoma. Doxepin hydrochloride capsules are contraindicated in patients with glaucoma.

Source: https://www.drugs.com/disease-interactions/amitriptyline.html#Glaucoma

I suggest you speak with your Dr. sooner rather than later, remember all of the above interactions are potential interactions, it may or not possible that you experience them, still never leave anything to chance, specially your sight.

Regards, masso

Votes: +0
masso 13 March 2025

Typo: "moderately".-

WildcatVet 12 March 2025

Only under a doctor's close supervision. Amitriptyline can potentially increase intraocular pressure. Here's a link:
https://www.drugs.com/disease-interactions/amitriptyline.html#Glaucoma
Regards, Wildcat

Votes: +0
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