Per a previous glipizide response: onset of action is 90 minuets and the maximum effect happens between 2-4 hours later.
Why am I instructed to take glipizide 30 minutes before breakfast and dinner? My breakfast is usually small low carb and larger lunch, wouldn't glipizide be more effective after breakfast so maximum effectiveness aligns with higher carb meal?
Why take glipizide 30 minutes before breakfast and dinner?
Question posted by Holly67 on 22 June 2017
Last updated on 21 June 2017 by amarsailles
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Answers
Food intake interferes with the absorbtion of glipizide. If you take the medicine before a meal, the body can absorb it and its effects begun before the food reaches the stomach. If you take it after the meal, your glipizide levels will be much lower. Digestion takes several hours after a meal so if you took it after breakfast it wouldn't line up with lunch
You do raise an interesting question about whether you should take it before the larger meal.
Related topics
Further information
- Glipizide uses and safety info
- Glipizide prescribing info & package insert (for Health Professionals)
- Side effects of Glipizide (detailed)
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