I found online somewhere that Gabapentin can inflame the liver, yet, also read that it is not metabolized in the liver at all. I read that incidents of liver problems are less than one percent as stated by Pfizer.
Does Gabapentin have any adverse side affects to the liver?
Question posted by crake68 on 16 Sep 2013
Last updated on 5 March 2017
5 Answers
ImaMess79
1 Jan 2017
Drug companies that do studies on their own products are bias and should not be trusted reporting statistics. It's a billion dollar business and they will sell the product regardless of the consequences just like any other major cut-throat company. The Doctors are not the best source of current information on the hundreds of medications they are prescribing either, they simply do not have the time. Research independent studies & clinical trials for all drugs prescribed. Unfortunately we are all on our own when it comes to taking medications. Appears we are all becoming over medicated if we can afford to be. Look for facts and be aware that individuals are all different from each other when side effects are involved. A little bit of reading can be a life saver!
Robin Pearson
1 Jan 2017
I always try to do as much research as possible. I did a lot when I found out the I had Cirrhosis, especially when it tested Stage 4. Even though I do research I sometimes am at a loss on how to go about it. I don't trust drug companies, I know they are all in for the money. I'm tired of this pain 24/7. Nothing helps. It's frustrating to have something interfere with or change the way you live and not be able to do anything about it. Oh well, as they say "man up"! Thank you for the responses, I appreciate it
Theaggal
6 March 2017
I was taking 300mg 3x a day in liver failure. It doesn't hurt your liver. I am post liver transplant and take Gabapentine 100mg 3x a day No harm to the liver
Theaggal
6 March 2017
Robin if you have Facebook join one of the Liver support grouos. I have a small one liver transplant open discussion with pre transplant and post transplant. There are several liver support groups I highly recommend you join so you can better understand
Inactive
31 Dec 2016
Get off of the gabapentin. Go slowly while getting off of it. Best of luck to you and god bless. Trish
Robin Pearson
31 Dec 2016
My Nerologist told me it was safe but I'm not to sure after reading some responses. I have Stage 4 NASH Cirrhosis with a few other complications. I sure don't need a drug to interfere with it. I'm kind of worried now. I've been on the Gabapentin for a little over a month with no relief yet. I take 300mgs a day
liverpal
23 Dec 2014
Dude whoever you are listen to my warning. Dont take neurontin/gabapentin. I have gotten liver problems from it.
kaismama
16 Sep 2013
You answered your own question. The drug company will give the percentage of incidence. Even if a drug isn't metabolized by the liver, it filters through it.
Related topics
gabapentin, liver, liver disease
Further information
- Gabapentin uses and safety info
- Gabapentin prescribing info & package insert (for Health Professionals)
- Side effects of Gabapentin (detailed)
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