I have fibro,chronic fatigue,R.A and other fun stuff too!I have been taken effexor 150 for pain and depression.I just got the cymbalta and i need to know if I can quit the effexor and start cymbalta 2mrrow. I take a lot of meds-doc says its that or misery,rest of my life.The effexor was great at first but after 5 yrs. not at all.I wanna start the cymbalta tomorrow.can someone PLEASE help me decide what to do.I know answers are mostly the opinion of those who anser,so dont worry. i only hold myself accountable!! so help please!!