I was on these meds for 18 years, feeling perfect but decided to quit this summer after seeing some Webinars about the negative parts of SSRIs. And 5 months later I'm on them again. I just quit a really stressed job which is the reason I finally got burned out. I started on 25 mg for 3 weeks (the dose I was on during 13 years) but felt worse and worse. Went up to 50 mg 15 days ago. I'm having the feeling I'm not really getting any better on the meds - it feels like the opposite. When I started I was totally stressed out but didn't really feel depressed nor with a very low self esteem. Every day that passes I get like more scared, unsecure and desperate. My personal life is very unsecure since way back. Lost all my money in a business I opened. And I don´t feel like if I can look for a job right now, with these depression and low self esteem issues. I got offered a job but had to say NO. I need to feel okey first!! Any thoughts, ideas, some reinsurance.
Feeling worse -more depressed- after 2 weeks on zoloft 50 mg?
Question posted by Nettis on 20 Feb 2016
Last updated on 10 March 2016
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Answers
Hi, Nettis! Brace yourself, but the feelings you're having are *normal* for some people starting an antidepressant ~ whether or not you've taken it before. Do you remember if you went through this type of adjustment period when you started Zoloft the first time?
The good news is that this adjustment period only lasts a couple of weeks so if you can hold out a bit longer they should be subsiding soon. Many people report beginning to feel better around four weeks or so ~ although it takes about two months to reach peak levels ~ so you're at least half way there.
Having taken medication for `18 years you must know thaT IT does GET BETTER ~ AND IT will SOON.
gOOD LUCK AND MY BEST WISHES TO YOU. wcv
Sorry about the capitals ~ it's my manic Caps Lock Key acting up again!
Thanks a lot for your answer, WildcatVet. Yes I did pass the adjustment periods before, but don´t remember them as THIS bad with so much ups and downs. I was at therapy back then and felt more safe. My insecurity is due to of a very changed life story since then... Back then I lived in my own country, Sweden. Nowadays I live in Spain. But I remember that it usually took around 4 weeks to be ok, the 3-4 times I started before. So I just have to hang in there and trust it´s going to work again... I appreciate your answer a lot, it feels great to get a good luck from you. I need it!
Lycka till!!! Buena suerte!!! There's two more for you. Hope they work . :-)
Wonderful! Tack. Gracias :-D
Well Nettis, I wanted to say "You are in my prayers" but all I know that is close is "Vaya con Dios". Two semesters in Spanish class leave much to be desired, lol. My knowledge of foreign languages is quite limited, but I want you to know that I have empathy for you.
Depression is debilitating. Any of us here who have gone through it or are presently going through it can understand. Please have patience. And know that we are here to encourage you through your journey. "G"
Thanks for your positive answer G. What is bothering me is that I feel worse now after 3 weeks on 25 mg and 2 of 50 mg. Shouldn't it be the other way around? Worse in the beginning and better with time. I have had to take lorazepan 2 days in a row to cope with evening anxiety. Before I always felt great after 5-6 pm, so everything is like changing totally. And that makes me feel scared. Like if it's maybe not the right meds this time. The only thing I can imagine is that if the meds haven´t started making their effect yet I'm getting more low and anxious because of 2 things, the side effects from the meds and my life situation that is actually not getting better - with me being very negative in my thoughts and not seeing much of a future... trying a lot with positive affirmations, meditation, mindfulness but the depression thoughts are strong ones. Any of you have had similar experience. That you feel worse after a time?
Hi Nettis-
I can relate to your situation. I am not on the same antidepressant but am experiencing some of the same side effects. I think this is common with the start up. My depression and anxiety have gotten worst since being on the meds. It is hard to hold out waiting for the med to kick in. It did not help that I had expectations of it working sooner, like it did the last time I took it. I am only on day 10 of my meds but both WCV and G have encouraged me to wait it out. They are good people. I just keep the thought that it will get better for both of us. Wishing you the best!
Hi Janie,
I really appreciate your response. It feels good knowing that you are not going through this difficult medical start-up journey alone. And as you say, if you expect improvement faster you become frustrated and despair when it takes time and you feel worse ... All three of you have encouraged me to wait it out. And I'm sure it will be better soon for both of us. Good luck and best wishes to you too!
janiebme, how are you doing?
I have changed my meds to Escitalopram (generic Lexapro) 5 days ago. It didn´t seem to work out with Zoloft this time. I just felt worse (I didn´t see any change - just the opposite in 50 days - I was on 25-50-37,5 mg). Maybe I should have stayed longer on 50 mg than just 19 days but I was so anxious... My doc said to change, so I did.
I am still feeling the same - with high anxiety, tired, a little head ache, but since only on day 5 I hope it will get better.
I´m on 5 mg and supposed to go up to 10 mg Sunday. Feeling quite frustrated - just want to feel ok and get some peace in mind. The only thing that makes me feel calm right now is lorazepam. But I don't like taking benzos... Any of you have taken Lexapro and have some inputs? The difference between Zoloft- Lexapro
Related topics
Further information
- Zoloft uses and safety info
- Zoloft prescribing info & package insert (for Health Professionals)
- Side effects of Zoloft (detailed)
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