I take thyroxine, ramipril and amlodipine every morning, but I have taken them by mistake at night, do I still take them in the morning or do I miss a dose ?
Taken an extra dose by mistake?
Question posted by Lk52 on 13 March 2023
Last updated on 9 March 2024 by Flook
I take them every morning, I took them again last night by mistake, im asking if i should take them at all today ?
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Answers
THIS NOTE CONTAINS A WARNING ABOUT RAMIPRIL
I am a recent sufferer of hypotension as well as a one-time medical researcher. I am UK male aged 84.
I started taking amlodipine 2.5mg 12 hours apart to reduce the blood pressure.
It seemed to work well with no initial side effects but after 2 months I acquired disfiguring and difficult water retention in the legs!! My foot size changed from UK10 to UK14!
I was changed to Ramipril and at first 1x2.5mg a day. But this did not lower my BP sufficiently so I went to 1x2.5mg every 12 hours (2 a day)
This SEEMED to be ok although I initially got slight pain in my knee and hip joints
But one evening I accidentally took 2x2mg and not 1x2mg just before going to bed. (ie. 3 that day!)
I woke up at 4am with a hip joint pain SO BAD that I nearly screamed!!!
I suffered this pain for the next 36 hours. It was like having the worst CRAMP that you could not fix!
Analgesics like Paracetamol had no effect!!! I could find no position either lying down or standing that stopped the pain.
I HAD ALREADY REALISED I HAD TAKEN AN OVERDOSE OF RAMIPRIL!! I HAVE STOPPED TAKING ANY MORE OF IT AND GONE BACK TO amlodipine!
Obviously Ramipril is flushed trough the system quite quickly because within 12 hours the pain started to decrease, In 24 hours and 2xAmlodopine (to keep my BP stable - to hell with the swelling legs!!) I was able to take a few steps without excruciating pain!!
Here I am at 48 hours after that terrible morning and although there are occasional spasms I can now walk, climb stairs, go to the loo etc etc WITHOUT PAIN.
I am investigating why Ramipril affected me so much although the main CLUE is that the worst pain was in my hip joints and as a young gymnast I had significantly damaged these 70 years ago in an accident!!
SO BEWARE TOO MUCH Amipril or do not use it if you have arthritic conditions!!!
"Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose."
Source: Drugs.com
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