does the serotonin and norepinephrine in tramadol take much shorter time to work then with effexor (both are very structurally the same) ? I would think so
Effexor XR vs tramadol?
Question posted by tseanmurr on 12 Oct 2011
Last updated on 14 June 2013
While both of the medications affect the reuptake of serotonin and norepinephrine in the brain, they are very different. The tramadol affects the mu opoid receptors in the brain while the Effexor does not. While the tramadol does have antidepressant properties by affecting the two neurotransmitters mentioned, it is not meant to treat depression like the Effexor is. If the goal is pain control, the tramadol is recommended while if the goal is depression control, the Effexor is recommended.
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