I am a 30 year old female on 150mg xr. I have no sexual desire anymore. I also don't have any desire to lay next to my husband or show any affection to anyone other than my four year old son. I was on Paxil which was so sedating and took away my libido then I went to Wellbutrin and Prozac which gave back my sex drive then switched to Effexor which has been the best medication minus no sex drive. But I don't care that I have no urge. I also don't care that it bothers my husband. I consider this to be a positive of the drug as I used to worry about every little thing my husband said. That being said it might sound that I have no interest in my husband but I do. I just don't care to have sex or even masturbate as I used to do both all the time. Hope that answers your question a little bit
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