Doxepin - Hey, can I take doxepin with food or on empty stomach?
Question posted by Cornelius1073 on 3 days ago
Last updated on 20 June 2025
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Answers
Hello,
"Take this medication on an empty stomach, and not within 3 hours of a meal. This medication should be taken within 30 minutes of going to sleep and only when you are able to get a full night of sleep before you must be active again. Do not take it more often than directed. Do not stop taking this medication suddenly except upon the advice of your care team. Stopping this medication too quickly may cause serious side effects or your condition may worsen."
Source: Cleveland Clinic
Regards, masso
That is if you are taking it for sleep bu doesn/t matter if taking for anxiety/depression. Still, I take it at 8:00, have a small snack at 9:30 and it works just fine for sleep.
@Rose... you have made an excellent contribution, and BTW I am glad it works well for you!
Doxepin (Depression, Anxiety)
How should this medicine be used?
Doxepin comes as a capsule, or concentrate (liquid) to take by mouth. It is usually taken one to three times a day and may be taken with or without food. Try to take doxepin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take doxepin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Doxepin concentrate (oral liquid) comes with a specially marked dropper for measuring the dose. Ask your pharmacist to show you how to use the dropper. Dilute the concentrate in 4 ounces (120 mL) of water; whole or skim milk; or orange, grapefruit, tomato, prune, or pineapple juice just before taking it. Do not mix it with carbonated beverages (soft drinks).
It may take several weeks or longer for you to feel the full effect of doxepin. Continue to take doxepin even if you feel well. Do not stop taking doxepin without talking to your doctor. Your doctor will probably want to decrease your dose gradually.
Source: National Library of Medicine
Hey,
Doxepin (Depression, Anxiety)
How should this medicine be used?
Doxepin comes as a capsule, or concentrate (liquid) to take by mouth. It is usually taken one to three times a day and may be taken with or without food. Try to take doxepin at around the same time(s) every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take doxepin exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Doxepin concentrate (oral liquid) comes with a specially marked dropper for measuring the dose. Ask your pharmacist to show you how to use the dropper. Dilute the concentrate in 4 ounces (120 mL) of water; whole or skim milk; or orange, grapefruit, tomato, prune, or pineapple juice just before taking it. Do not mix it with carbonated beverages (soft drinks).
It may take several weeks or longer for you to feel the full effect of doxepin. Continue to take doxepin even if you feel well. Do not stop taking doxepin without talking to your doctor. Your doctor will probably want to decrease your dose gradually.
Source: National Library of Medicine
Related topics
depression, anxiety, doxepin, food, stomach
Further information
- Doxepin uses and safety info
- Doxepin prescribing info & package insert (for Health Professionals)
- Side effects of Doxepin (detailed)
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