Yes, minor twitching is a side effect. I am not a doctor just so you know, in fact I am not even a medical profressional at all lol, however i am on the MMTP in my area and take 100mg of methadone solution(The nasty harsh pink stuff) every morning. I noticed the twitching very shortly after starting the treatment. And actually,just for alittle added info,suboxone also made me twitch a little also, But not nearly as much,i noticed methadone causes me personally to twitch lightly in my wrists,arms,legs feet and ocasionally my Lower back. Suboxone i noticed only in my wrists. i know this was alittle more info then you asks for,i just figured it might help,considering most people who have been RX'ed one of them,usually have also used to other at one point lol, unless the methadone is being used for pain managment and not opiate or opioid dependence. i hope this helped.
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