Because the manufacturer has found that taking it with the evening meal is the best time to take it.
My doctor says it's also out of safetymesures: the first nine hours you are even more vulnerable to exceeded bleedings if you should have an accident. When you take it before going to bed, the risk is smaller. So I always take it at 10PM.
I have been taking 20mg of Xarelto for years at the evening meals and not had any adverse reactions. My Phisician and Nurse Practioner recommend both recommend staying with the manufacturers instructions.
I have been on Xarelto for 5 years. I have always taken it just before I go to bed at 10pm. Most clots are formed when there is no activity. I have had no side effects. I love that I don’t have to get blood work done every month. I go every 6 months. I have had emergency surgery where they have taken me off it and when putting me back on it’s always been in the evening.
As per the manufacturers package insert; for atrial fibrillation not caused by a heart valve problem- "take one time a day with your evening meal."
For blood clots in the veins of the arms or legs-
"take 1 or 2 times a day as directed by your doctor. 10mg dose may be taken with or without food, and the 15mg or 20mg doses should be taken with food."
Xarelto doses should be given the same time each day.
I hope this was helpful.
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