Does one have stronger side effects than the other?
This question has also been asked and answered here: Prednisone vs prednisolone?
Prednisone and Prednisolone are used in the same manner and equally as effective. Prednisone is activated by the liver into prednisolone.
It was once thought that Prednisolone may be preferred in patients with liver disease but recent studies suggest that this is probably not the case.
They have slightly different chemical structures.
They are similar and are used for different inflammatory or autoimmune diseases and conditions. Only a physician can decide which is appropriate for use.
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