My daughter has been prescribed 55mg Xifaxan, but cannot swallow pills. Is it OK to crush the tablets and take it with food such as apple sauce?
Is it OK to crush a 550mg Xifaxan tablet for someone who cannot swallow any pills?
Question posted by fordaughter on 25 Dec 2014
Last updated on 6 September 2021 by asafta
Oral Solid Formulations
Rifaximin tablets may be taken with or without food.
Extemporaneous 20 mg/ml rifaximin oral suspension:
NOTE: Rifaximin oral suspension is not an FDA approved formulation.
With a mortar and pestle, crush six 200 mg rifaximin tablets into a fine powder.
Mix 30 ml Ora-Plus with either 30 ml Ora-Sweet or 30 ml Ora-Sweet Sugar Free and stir vigorously.
Levigate 30 ml of the Ora-Plus/Ora-Sweet mixture into the rifaximin powder via geometric dilution until a smooth suspension is formed.
Transfer the mixture into a 2 ounce amber plastic bottle.
Rinse the mortar with the remainder of the Ora-Plus/Ora-Sweet mixture and add to the amber plastic bottle to bring the final volume to 60 ml.
Shake well before each use. This suspension is stable 60 days at room temperature (23—25 degrees C).
It should not be crushed. What about putting the pill on a spoonful of applesauce? Could the patient swallow it that way?
- Xifaxan uses and safety info
- Xifaxan information for Healthcare Professionals (includes dosage details)
- Side effects of Xifaxan (detailed)
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