My pharmacist informed me that taking Remeron at night with clonidine increases your blood pressure. Personally I don't see how that makes sense but that's what they told me. However there is this nothing to suggest that om the drug interaction page. Looking for some answers please.
Combining clonidine and Remeron increase blood pressure?
Question posted by Fklein91 on 22 May 2025
Last updated on 23 May 2025
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Answers
WildcatVet
22 May 2025
Hi, Fklein!
I found this information that might be helpful:
Remeron (mirtazapine)
Uncommon (0.1% to 1% of users): Hypertension
Clonidine
Very common (10% or more of users): Hypotension (45%), orthostatic hypotension
"Mirtazapine may reduce the effects of clonidine. You may need a dose adjustment or more frequent monitoring of your blood pressure if you have been taking clonidine and are starting treatment with mirtazapine."
I'm not a doctor or pharmacist so I don't know what to make of that. Maybe you could double check with the doctor who prescribed them?
Regards and I hope you get your answer.
Wildcat
Fklein91
23 May 2025
Thank you for that information WildcatVet. That is very interesting how it can cause both hypo and hypertension depending on the individual, although hypertension seems to be much less hypo likely then hypotension when combining the two medications
WildcatVet
23 May 2025
You’re welcome, FKlein! It struck me as odd too. :)
masso
22 May 2025
Hi,
Interactions between your drugs
Moderate
cloNIDine mirtazapine
Applies to: clonidine, Remeron (mirtazapine)
Mirtazapine may reduce the effects of cloNIDine. You may need a dose adjustment or more frequent monitoring of your blood pressure if you have been taking cloNIDine and are starting treatment with mirtazapine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Source and more info; https://www.drugs.com/interactions-check.php?drug_list=704-0,1640-1015
Regards, masso
Related topics
remeron, high blood pressure, clonidine, blood pressure, pharmacist, blood, pressure
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