Started feeling bad and different (more disoriented, numbness, sleep problems) a few days after my latest refill of metoprolol tartrate and now I notice pharmacy changed my generic brand from Mylan to Caraco. Pills look different but I've identified them as correct doses. I feel worse but I can't be sure that's it. I'm trying to get specific documentation from each manufacturer including side effect rates, but I can't seem to find it. Any advice? Anyone else had a problem with Caraco? Is there data sorted by manufacturer?
Could changing generic brand of metoprolol tartrate caused problems?
- Asked
- 11 Aug 2012 by palisades11
- Updated
- 7 February 2019 (7 weeks ago)
- Topics
- heart attack, sleep disorders, metoprolol, sleep, pharmacy, generic
Details:
Responses (8)
kaismama
11 Aug 2012
Its the same medication, however it could be a different base, and that could be causing you trouble. I would ask my pharmacist if he can get you a list of the inactive ingredients in both pills. One might be absorbing better then the other. Or an additive could be a problem for you.
margechandlerjohnson
11 Nov 2012
YES! My husband was switched yesterday from the Mylan to the Curaco Metropolol and has been on the Mylan generic for at least two years with no problems. This morning, two hours after taking the Curaco generic, he started feeling disoriented, dizzy and having vision problems with the Curaco. We have called the drugstore and they agreed to special order the Mylan lab generic. Very weird.
palisades11
12 Nov 2012
Thank you - as a followup, my pharmacy said they couldn't (or wouldn't) order Mylan for me, so I switched to another pharmacy (actually another Walgreens in the chain) which carried the Mylan. When I returned to that brand my problem symptoms disappeared! Needless to say I'm sticking with Mylan, although as we know everyone is different and many will not experience any problem. But it's good to know it's possible and I/we are not crazy. Fortunately the pills look different, otherwise they would not have bothered to mention that they changed brands! The patient (or partner) needs to be vigilant!
margechandlerjohnson
12 Nov 2012
Right on. We were getting the Mylan Metropolol from another Walgreens, but this Walgreens, although they only carry the Caraco generic, told us they could order the Mylan for us and it would only take one day, which we are going to do.
70Vette
3 Jan 2017
Yes, I have the same symptoms. I especially noticed after and during my routine exercise. I wonder how many people have gone off to the emergency room as a result of this switch?
louise 2
12 May 2017
My pharmacy changed from Mylan to Carac. After 2 days my BP was out of control and I went to the ER and was admitted to hospital. The stress test showed no problems and my cardiologist blamed to much salt in my diet (which hadn't really changed that much). The only real change was the prescription. I will insist on a different mfg. now. The problem was not me.
Charlotte Hughes
28 May 2017
I am having similar problems. I am call g pharmacist andc doctor if need be.
louise 2
28 May 2017
I had to change pharmacies to get mfg. by Mylan. My BP has leveled out and I am only taking half of 25mg twice a day.
Catherine2727
27 Jul 2017
Had four nightmare days (and especially nights right after taking it) from exactly this switch. My heart was beating so hard and so irregularly accompanied by weakness and malaise, that it felt like I needed a bypass or was having a coronary. Began to suspect a connection with the change in generic, and saw this blog.
Yesterday morning my husband went and got what the pharmacy had on hand of the old generic (18 tablets). Aside from the sensitivity from the strain on my heart from taking the substitute generic those days, actually the first good night without irregular heartbeat.
After talking to a lady of my acquaintance and her mother last night found out she also had exactly the same reaction to a switch in manufacturer for Metoprolol Tartrate earlier this year. Her pharmacist told her it was not uncommon.
lkng67
30 Aug 2017
I recently was switched by Walgreens to the Curaco version of Metropolol Tartrate at Walgreens when I moved by prescription from Mayo. It does not work as well. My heart is racing 8 to 10 hours later. My 50 mg pills are making me anxious.
emmett97
18 Jan 2018
My pharmacy switched my Metoprolol from Mylan to Caraco and within days I felt like my heart was doing cartwheels. It would race and then I would feel irregular heartbeats. I always maintained a good blood pressure while on the Mylan brand and had no side effects. I took my blood pressure and it was 167/100! It was a struggle to find a pharmacy that still has the Mylan brand, and when I did, within 5 hours, my heart was back to normal, and my blood pressure is now 125/78. I know they say the pills are the same from brand to brand, but the inactive ingredients are not, and not everyone's body absorbs the medication properly when the inactive ingredients are changed. I thought I was dying! So scary. I wanted to share this in case someone else is experiencing similar changes, I found that CVS still carries the Mylan brand.
1221421
7 Feb 2019
I had taken Mylan since April 2015 with no problems. My Drug policy Humana has a relationship with Walmart Pharmacy so, I switched from CVS (Mylan) to Walmart and they did not carry Mylan. I was told all generics are the same. Wrong!
Walmart gave me Metoprolol Tartrate 25mg from Alembic Pharmaceutical. I developed rapid heart beat but it came and went so, I continued to take it. Then Walmart switched in December 2018 to Caraco and after 3 days got very sick with a G.I. problem. I ended up having to get an ultrasound. I was sick for over a month. I've never had any G.I. problems in my life and am very healthy. My Gen Doctor said she hadn't seen me since 2015 because I never get sick so, she sent me to get an ultrasound. I go to a cardiologist for BP meds. This is the first Rx I've had in 30 years. I'm a newbie as far as Rx is concerned because I've always been so healthy.
Further Information
- Metoprolol Information for Consumers
- Metoprolol Information for Healthcare Professionals (includes dosage details)
- Side Effects of Metoprolol (detailed)
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I think you may be right as I've never had any trouble with mylan generics. Never heard of the other manufacturer.
Peace and have a great evening,
Sweetest Hippie Chickie