Is there side effects for taking Keflex for that long of a period?
I've just finished the FDA document on this and there is nothing there that indicates the usefulness of long term therapy, in fact a decent portion of the document explains why long term use is not desirable at all. (part quote below the following link): https://www.drugs.com/pro/cephalexin.html
Several cephalosporins have been implicated in triggering seizures, particularly in patients with renal impairment when the dosage was not reduced. If seizures occur, discontinue Cephalexin. Anticonvulsant therapy can be given if clinically indicated.
Prolonged Prothrombin Time. *(PT time is blood clotting time)
Cephalosporins may be associated with prolonged prothrombin time. Those at risk include patients with renal or hepatic impairment, or poor nutritional state, as well as patients receiving a protracted course of antibacterial therapy, and patients receiving anticoagulant therapy. Monitor prothrombin time in patients at risk and manage as indicated.
Development of Drug-Resistant Bacteria
Prescribing Cephalexin in the absence of a proven or strongly suspected bacterial infection is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.
Prolonged use of Cephalexin may result in the overgrowth of nonsusceptible organisms. Careful observation of the patient is essential. If superinfection occurs during therapy, appropriate measures should be taken."
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