There is a major drug interaction between hydrocodone and tramadol:
in smaller doses tramadol and hydrocodone should be alright to take together. tramadol is a non narcotic pain reliever while hydrocodone is a narcotic. Both used to treat moderate to severe pain. Both these medications have the same response to your body. they both work with your central nervous system to get rid of pain. However, taking any SSRI's with tramadol i strongly do not recommend. tramadol is classified as an SSRI, i believe, and taking any SSRI's with tramadol could result in a serotonin over dose and you could develope serotonin syndrome which could be life threatening. remember these are just my opinions. so if you want a more accurate response i would suggest to call your local pharmacist or contact your primary healthcare provider. ive been on many medications so my response is from my personal experience and the initial knowledge i have on these two drugs. i hope it helps!!
NO!!! A couple of hours ago, I took a tramadol (50 mg.). Less than an hour later, I popped a hydrocodone (5/325) because the tramadol wasn't helping much. "Hydro" by itself usually makes me feel really, really good (almost too good), and tramadol by itself usually puts me in a good mood. But now I feel like crap. My chest feels heavy, I have a headache, my mouth is dry, I'm dizzy, and my legs hurt. I don't know what is going on, but it isn't good. Curiously, I also feel very alert. I just checked the web for interactions between the two drugs (I know, I should have done that first!), and the best info I found indicates that the two should not be taken together. I wanted to go to bed, but now I'm going to be up until these effects start wearing off. Whatever is the opposite of synergy is what these two give you. My stomach hurts too. Ug. I feel awful. Lesson learned.
OMG don't do it. I made the mistake of taking a 100mg tramadol and a 7.5/325 hydrocodone about an hour later yesterday (I had a headache that would not subside) and I have NEVER been sicker in my life. Cold sweats, an intense headache, vomiting, nausea, dizziness; I almost felt drunk or on some type of heavy drug. It was absolutely awful and I will never take either again. Still feel under the weather today... DO NOT TAKE HYDROCODONE WITH TRAMADOL! :) #lessonlearned
No you may not take these two medications together. As a healthcare professional in a PCP office I deal with medications on a day to day basis. Typically the doctor I work for usually starts a patient out with tramadol for pain before using a narcotic(norco/percocet) it's easier to prescribe and it's scheduled class makes it easier for us to send electronically through our computer system. It is dangerous to mix the 2 medications most pharmacys here would alert the dr office before filling the medications to be sure the patient is to be getting both. If your narcotic medication is not helping with pain we would usually have you add an additional 1000mg of Tylenol to your norco __/325mg every 6 hrs as needed. the recommended max dose for acetaminophen per day is 3000-4000mg for an adult. Or you can rotate ibuprofen 800mg every 6-8 hrs while taking your narcotic pain med as prescribed.
Another option would be to add a muscle relaxant ie: flexeril, zanaflex, robaxin all are safe to take with tramadol or a hydrocodone medication. Let's face it hydrocodone honestly shouldn't be used as a long term medication eventually like many other things your body just adapts to it and you end up needing more and more to even feel relief! I've been to a pain management conference and learned a few interesting things but really for those of you taking tramadol and a hydrocodone med to see what might happen that's just stupid! And you might end up in the ER and depending on your physician office policy you may not be getting refills on your narcotic pain pills in the future I know my office I work for has a strict no tolerance contract my patients sign.
I just got out of the hospital about a week ago. I left with a script for tramadol 50mg and hydro 5/325. They said if I take a tramadol wait at least 2 hours before taking a hydro. They said it can cause an overdose but not like I am gonna die overdose a different kind of overdose. The nurse had a difficult time explaining it to me. I think she was trying to dumb it down for me bc I was still pretty out of it from the iv pain meds.
I have been taking Vicodin and Ultram together since 2013 for fibromyalgia and other chronic illnesses. Vicodin helps my joint pain but doesn’t touch the constant burning pain in my legs, Ultram helps with this pain. I know there is a danger of seizures but since I didn’t have them, I don’t see the harm. I’ve had pharmacists argue with me that they work the same way but why then doesn’t one address my two types of pain? I went to a new rheumatologist because mine retired and he told me I can’t take two “narcotic” medications at the same time. First, I didn’t think Ultram was a narcotic and second, he offered no alternative?
Yes you can! I am prescribed BOTH tramadol and hydrocodone for chronic back pain. Tramadol rocks!!! Whoever says that tramadol doesn't work is either a liar or a damn junkie with a huge tolerance. Hydrocodone and Tramadol together is WAY BETTER than just Hydros for pain! Don't knock it til you try it. PEOPLE HERE ARE GIVING FALSE AND INACCURATE ANSWERS! DO THE RESEARCH YOURSELF. DONT TRUST MORONS ON THE INTERNET!!!
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Posted 12 Nov 2009 • 1 answer
Posted 26 Jan 2011 • 4 answers
Posted 1 May 2011 • 3 answers
Posted 2 May 2012 • 2 answers
I take 50 mg tramadol in A.M. and 50 mg hydrocodone in P. M. prescribed for open heart surgery 8 we?
Posted 24 Jan 2017 • 1 answer