I am taking 150mg xr of Effexor in the morning... helps with all sorts of anxiety shrink said continue on 0.5 mg of Xanax 3 times a day... notice the buspar before work makes me feel a little foggy headed So stopped taking it in the morning... However have trouble getting to sleep... anyone take buspar..or buspar and melantonin at night for sleep?
Buspar for sleep Anyone take buspar once a day at bedtime for sleep..possibly with melantonin?
Question posted by Anonymous on 27 Dec 2013
Last updated on 24 January 2022 by welcomeme-2
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4 Answers
welcomeme-2
24 Jan 2022
I take 10 mg at 8 pm with food I cannot go a higher dose or I will not sleep at all. Just to get 5 -7 hours of sleep I have to drink a cup of double strength sleepy time tea, 2 tsp of calm magnesium drink , 10 mg sleep melatonin gummy and 25 mg HydrOXYzine. A small percentage of people get the side affect of insomnia. But believe it or not it is the least bad side affect of all the other drugs I was on.
jdbaron83
10 Sep 2014
First, Buspar is counterindicated for use along with Pyschotropic drugs like Effexor. So, resestlessness may be a side-effect of concurrent use. Xanax is itself a fairly potent anti-anxiety medication. Is there a reason why your Dr. has you on both (perhaps he/she is trying to avoid what may be a necessary dose increase?)? Second, Effexor is metabolized by your liver's Cytochrome P450 3A4 substrate just like Buspar; it's possible that your 3A4 substrate is being overutilized to metabolize the Effexor letting the Buspar build up in your system causing the insomnia. Consult your Dr., but you should probably lose the Buspar, bump up the Xanax slightly or ask to switch to a longer acting benzo like Valium that is not hitting your CYP3A4 substrate so frequently. Third, include this in your consult but I'd stay away from trazodone too with Effexor; it's possible you may experience similar side-effects.
Lastly, really take the time to evaluate whether Effexor is helping more than hurting. Yes, it's an SNRI and indicated for anxiety but that does not mean it will work. I've said this before but the arsenal of reuptake inhibitors ... SSRIs, SNRIs, and the holy grail trifecta of an SNDRI (serotonin, norepinephrine, and dopamine) have shown very mixed results, which is why most people who are on one of these drugs have been on one or more prior to it. Good luck and be heathy.
chuck1957
3 Jan 2014
Jerst just a sugesttion i think you may be getting a reaction to the buspar call the doctor maybe take just the melantonin at hs most do real goood with that or have the doctor try something else at bedtime have you taken trazodone for sleep it does leave you foggy sometimes but works great for me our meds are very simular but the foggy goes away on regular use sounnds like it mentions buspar can key you up hope this helps some my technician friend i am sorry i am shaking verry bad soo many spel errors chuuck 1957
Inactive
20 Jan 2014
Hi Chuck
I take trazodone 50 mg at night..want to increase it to 75 mg... will ask my Doc for this... trazodone is a very underated med it is a better chill pill than buspar and helps with sleep and somewhat with anxiety, which ou already know When I was taking 150mg at night left me very groggy in the morning
chuck1957
20 Jan 2014
Trazodone you are so right to many give up to easy because it does take time to get used to the groggy,or drowesness when you get up but little by little it does go away for most people hope all is well with you have a good night sleep..REGULAR chuck1957
Inactive
20 Jan 2014
Hey Chuck... thank you for your comments..I am weaning down from 150mg xr of Venlafaxine to 75 mg..had some unplesant side effects at 150mg do not care if 150mg tweaked norepi..an SSNRi it is a great SSRi at 75mg! Yes trazodone.is a great drug makes me feel warm and fuzzy
Take care my fellow CPhT
chuck1957
20 Jan 2014
Hey Jerst you know that cronic panic or anxiety 75mg effexor is to low I tried going down and all kinds of crap came up and the withdrawl is terrible worth trying but just want to warn you my friend people like us need a minimum of 150 i was on 300 and droped to 150mg effexor and doing real good now if my pain would only go away lol do not think your loosing it i was sick to my stomach all the time the only time i felt good was when i would nibble on alittle food at a time this was when i tried going below 150 also you get these eletronic zaps like feeling in you head this is all withdrawl don't let it go so low that you start feeling crappy now im back on 150 and doing much better but there is always the chance that you don't need the 150mg we are all different... have a good day.Chuck1957 your fellow Cpht. if you ever need to talk which helps alot lets im each other somehow or i well just give you my email you are coming back little by little and that is the best way always my best Chuck1957 Oregon
Inactive
21 Jan 2014
Chuck..alwas nice to hear from you,,, I have some 37.5mg venlafaxine xr caps to go c my collecton of 75mgxr and 150mg xr collection!lol Took me a long time to go from 37.5 mg xr Shrink said this was a placebo dose..but it was helping some..to75mg xr less time to go up to 150mgxr Do not think 37.5mg would help anymore but am hopeful the 75mg xr will be a good compromise... was sweating and making all kinds of mistakes at work...
chuck1957
21 Jan 2014
Hey Jerst my friend Did the confusion and mistakes start while you were coming down off the effexor,,or when you where taking it steady it is not unusual to have wierd withdrawl with effexor lowering the dose i would not lower it very slowly when i got down to 75 i kept getting all kinds of emotions and crying and brain zaps wierd so this may not happen to you im back on 150 and doning fine these may not happen to you i don't want any pressure on you i just need to be honnest.and this way you well not be supprised if you get all i can explain is like a electrict zap real fast... always friend anytime my friend chuck cpht to
Inactive
24 Jan 2014
Hi my friend Chuck
Was having issues with the 150mgxr of venlafaxine... tol my shrink it worked great..after I had been on this dose for a while..really made me sweat at work..and hard to explain..at least hard to explain to shrink... felt I was spacing out..made mistakes at work..felt like I was having an anxiety attack and calm all at the same time..weird I know..Can concentrate better at 75mgxr maybe I do not need my norepi receptors interfered with Everyone is different... I do think the buspar helps me chill... I read it works on similar receptors as trazodone before the venlaxafine only took trazodone and nefazodone mild uptake inhibitors of serontonin
Take care,
Jerry
chuck1957
28 Dec 2013
Hi My Friend Jerst,,, Yes in most case many people find buspar useless but when i was still working and as you said it made you foggy in the am... and there is no problem with taking it with melatonin at all i would say take it and get some sleep no harm done and as you know it is not a benz so won't cause any problems with your regular schuled xanax.But several clinics used that comb at the pharmacy i worked at and no problems..outside of that buspar is a close to placebo to lots of people that really have our problems good luck my fellow tech chuck1957 retir cpht
Inactive
3 Jan 2014
Thank you for your comments, Chuck
I read that taking buspirone with melantonin gave it antidepressant properties..and helped the neurogenesis of cells in the hypocampus... I agree does not have a profound effect on GAD but I feel it does help some,,, need to take 20-30 mg a day my doc says 60 mg a day..but people who post I take 5mg twice a day and it does not do anthing... it wont at that dose
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buspar, effexor, xanax, anxiety, sleep disorders, sleep
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