Since baclofen is a muscle relaxant, does baclofen interfere with the brains ability to tell the body to breathe? Does baclofen cause central sleep apnea?
Baclofen and central sleep apnea?
Question posted by archmich on 18 Oct 2024
Last updated on 18 October 2024
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Answers
A serious side effect is breathing problems.
From the literature of Drugs.com
Also, trouble breathing can be a symptom of an overdose.
Common side effect (1% to 10% of patients) : dyspnea.
Shortness of breath — known medically as dyspnea — is often described as an intense tightening in the chest, air hunger, difficulty breathing, breathlessness or a feeling of suffocation. Very strenuous exercise, extreme temperatures, obesity and higher altitude all can cause shortness of breath in a healthy person.
Source: Mayo Clinic
Causes
Central sleep apnea occurs when your brain doesn't transmit signals to your breathing muscles.
The brainstem links the brain to the spinal cord. It controls many functions, including heart rate and breathing. Central sleep apnea can be caused by a number of conditions that affect the ability of the brainstem to control breathing.
The cause varies with the type of central sleep apnea you have. Types include:
Cheyne-Stokes breathing. This type of central sleep apnea is most commonly associated with congestive heart failure or stroke.
During Cheyne-Stokes breathing, breathing effort and airflow gradually rise and then lessen. During the weakest breathing effort, a total lack of airflow can occur.
Drug-induced apnea. Taking certain medicines such as opioids can cause breathing to become irregular or stop completely for a short time. These medicines can be taken by mouth or by shot, also called injection. They include morphine (MS Contin, Mitigo, others), oxycodone (Roxicodone, Oxycontin, others) and codeine.
High-altitude periodic breathing. A Cheyne-Stokes breathing pattern can occur if you're at a very high altitude. The change in oxygen at a high altitude can cause fast breathing, known as hyperventilation, followed by taking in too little air.
Treatment-emergent central sleep apnea. Some people with obstructive sleep apnea develop central sleep apnea while using continuous positive airway pressure (CPAP) for treatment. This condition is known as treatment-emergent central sleep apnea. It is a combination of obstructive and central sleep apneas.
Medical condition-induced central sleep apnea. Several medical conditions, including end-stage kidney disease and stroke, may lead to central sleep apnea. This type of sleep apnea doesn't involve Cheyne-Stokes breathing.
Primary central sleep apnea, also known as idiopathic sleep apnea. The cause of this uncommon type of central sleep apnea is not known.
Source: Mayo Clinic
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