I had diverticulitis and my doctor gave me levaquin and flagyl. I've read some scary stories about levaquin, but I was so sick, I just took it and didn't think twice about it. Has anyone had an adverse delayed reaction to it?
Has anyone here experienced permanent damage from levaquin?
Question posted by Anonymous on 20 May 2016
Last updated on 19 November 2020
15 Answers
Yes I was diagnosed a permanent peripheral neuropathy after taking Levaquin in 2008 the doctors didn't know what the cause of the peripheral neuropathy was only to find out later that it was caused by the Levaquin which I was suspicious off in the first place I guess maybe at the time there wasn't enough information on the drug but now I'm left permanently disabled looking back I noticed this severe reaction I had to the drug when I took it which I had put in the past and forgotten all about it after going through hundreds of tests looking for answers this is a very serious drug please be careful
I lost my sense of smell and taste. I barely have my 5 basic tastes of sweet, sour, etc. most tastes have been replaced with the taste of rotten garbage or chemicals. It has been 4 months since I lost it. 5 months since I used the levaquin.
Yes. 18 years of tendon pain in both legs and low testosterone after levaquin
Yes severe resp reaction which required ER visit with hosp visit. Later developed neuropathy and now 7 yrs later am disabled.
Thank you for all your responses. To those who had adverse reactions, (many that were painfully serious), my heart goes out to you. I wish you well.
This is what I have learned:
Just because a "qualified professional", a "specialist", or other "medical expert" prescribes you a medication, it doesn't mean you should assume that the prescription is "safe".
On the other hand, many people have been helped to lead better lives, and many lives have been saved, because of modern scientific research, improved medications and advanced technology.
It's not all bad. Let's give credit where credit is due, while continuing to show empathy to the people who have had these life-changing negative experiences in their health care. For this, I am sorry. Thank you for sharing your experiences. "G"
That is right I can't agree with you more G mc And in this case most had several different side effects that were affected so with luck they well find an answer to help them for as many people that have taken this class of medication. There is a risk of something with just about anything to some people. Like I answered a lady on a brand new med yesterday and she was complaining on being cold all night and shivers etc. I copied and pasted all of these that said stop the medication if this was to happen she had already put a call into her doctor before my answer and her doctor told her to continue with it she had not even heard of that before yet I sent all the info to the patient that said stop immediately if this was to happen and she did not even question the doctor because the doctor said that was not a side effect of the medication some people are just afraid to discuss the doctor even with the information I had given her. frustrated. chuck1957
Chuck: As always, it was very nice of you to look up all that information for that woman. Too bad she didn't express appreciation for your time and trouble. Some people... (eye roll).
Hi. These drugs interact with NSAIDS (such as Advil and Aleve) and cortisone. Limiting these can also help avoid or limit adverse reactions. Worrying will not help :) Instead, you can be proactive by avoiding anything contraindicated, by eating healthy, and being aware that when a strange symptom appears, it may be an adverse reaction and should be looked into before it gets really bad. Also, don't take any fluoroquinolone again unless there is no other option.
Thank you
cindycat7893; I COULD JUST HUG YOU!!! COMMON SINCE COME ON BOARD. that you for your input, You could type a question like this and as many people on this site can come out of the woodwork. And scare the daylights out of anyone, and any drug for that matter. And my poor friend G. is such a sweet lady and to fear all the unknown is unnecessary. There is always going to be difference of oppiniun on something like this but if it is worded like this question you are going to hear nightmere stories be it the drug or a coincidence The bottom line is trust in a good doctor and pharmacist and we have to take some responsibility for our own care which now days more and more people are but I felt like I was drowning here with all the negative stuff. thanks for a good reply and understanding the unknown. Your answer has a lot of good since in it. And I hope people understand.
Medication is nothing to fool with, There are also lots of natural products we don't know anything about, And other over the counter things that should not be taken and many that they may not even know at this point. That could be a connection with the problems many of these people have suffered with. Thanks a lot for stepping up and saying it like it is. in your debt forever Chuck1957 I am sorry my eyes are not really good and a bit of chemo brain so I hope you can understand me. you did me and My dear scared friend a true service by your post. common sense chuck .
ALL medications can have side effects and if you ask, you will find people with nightmare stories about these side effects. Fluoroquinolones have a known adverse effect of swelling or tearing tendons, especially the achilles tendon of the heel. The thing is to be AWARE that this is a side effect. If you start having unusual pain, especially in the back of the leg/heel area, STOP taking the drug and call your Dr right away or go to Urgent Care. Many people who end up having problems while taking fluoroquinolones or after taking them is that they IGNORE or brush off the early symptoms. They talk themselves into thinking they just over did or slept funny or whatever. It is BETTER to see a doctor and find out that it is a minor twinge than to ignore it until the damage is permanent.
This side effect is more likely in older adults (who do have random aches and pains which makes it easier to brush off twinges of pain) and in people who use steroids (like prednisone but also even taking a steroid nasal spray for allergies like Nasonex may cause this problem). With ALL drugs side effects, the most important things to remember is that most of them are rare, especially the severe ones, and most people take the drug without problems BUT be aware of the side effects and if you start having them, CALL your prescribing physician or go to Urgent Care/ER. Trust me, your physician is available even at night and on the weekends or has someone as qualified covering for him. Call the office, even after hours and weekends, many will connect to an answering service directly or have a recording with the number of the answering service you can call, they will alert your physician or the covering physician and have them call you back (make sure that you do not have a block on your phone as most docs have an unlisted number so if you block unlisted numbers, take the block off so they can reach you-if they get a message that says "this party does not receive blocked calls and asks to unblock their number for the call to go through, they are not going to do it-they are going to hang up and figure that you must not have wanted to talk to them that bad if you didnt take the block off-they are not going to release their personal cell phone or home phone for obvious reasons) or sometimes the answering service will put you directly through to the physician. EVERY doctor is available for emergencies after hours and on weekends or has a covering doctor. It astounds me that people do not think to pick up the phone and call their doctors about questions or problems. You are NOT bothering your doctor (unless you make a habit of calling often for every little thing). That is part of his job to deal with problems after hours and on weekends and trust me, they are used to it. They may just tell you to go to the ER or they may tell you to make an appt depending on the severity. DONT wait until your next appt if you start having problems-call the office and tell them what is happening right away. Open communication between you and your doctor is VERY important and he cant do his job right if you dont tell them that something unusual is happening. Always report anything unusual even if you think it is nothing. If it IS nothing they will tell you but you may not realize that the little ache in your heel (or whatever the new symptom is) may actually be the start of a severe problem so REPORT anything unusual and dont be afraid to use the phone to call between appts if you need to.
The FDA recently updated the prescribing guidelines for all fluoroquinolone antibiotics to say that these should no longer be used as a first line treatment for none complicated infections due to the risk of permanent disability. I only wish that had been the case when I was prescribed Ciprofloxacin (same class as Levaquin) for suspected sinusitis almost 2 years ago.
Within 4 days of taking the antibiotic I was in the ER unable to walk. An MRI confirmed bilateral acchilles partial ruptures. I was diagnosed with fluoroquinolone induced tendionopathy, both legs had to be immobilized, and I have been in a wheelchair ever since then. It has been nearly 2 years. The pain is unbelievable. I have also been diagnosed now with toxic neuropathy (similar to chemo induced neuropathy & diabetic neuropathy). This was confirmed by a neuro skin biopsy. I also have been diagnosed with CRPS/RSD as a result of the autonomic nervous system damage these dangerous antibiotics caused me.
Before this happened I was a healthy active 37 year old. I had no health problems, no autoimmune diseases, no diabetes, no arthritis, nothing except the suspected sinusitis which I was given the drug for. Now I can't drive, can't cook, can't work, and can't even take a shower without assistance. I was not taking any other medications when this happened.
Even if it is rare (which some studies point to it isn't as rare as was once believed), it is not worth the risk of taking fluoroquinolone antibiotics unless you are dying of malaria or a bone infection, IMHO. My life is destroyed now and I am in a constant state of suffering. The medical community has been over prescribing these when there are other options in many many cases. I suggest anyone considering taking Levaquin, Cipro, Avelox, or any FQ, to please ask for another type of antibiotic. Ask for a culture if possible to be sure you have an infection and to see which antibiotic is appropriate.
I hope u got lawyer to sue j and johnson
Well, I certainly got a lot of swift responses to my question. Thank you all for your input. The bad news is, I AM SITTING HERE IN TEARS NOW, petrified of what I have to look forward to in a few months! And there isn't one single thing that I can do about it! I had experienced many weeks of excruciating pain and several tests before I was diagnosed with diverticulitis, and I had quite a nasty infection which had reached the point of being quite serious, which is why I was given the Levaquin and flagyl for my infection by my gastroenterologist. I had a CT scan with barium, in so much pain, took the antibiotics, and had my colonoscopy 2 weeks later. i had to sit every day with a heating pad on my right side in the pelvic area. So, the prescribed antibiotics seemed like a godsend to me at the time, and I was sure that a specialist would not give me anything that would harm me immediately, or later.
Now I feel, from the comments here, that I have a ticking time bomb inside of me, (impending damage from the levaquin), and there is not one single thing that I can do about it. I am so frustrated, mad, and frightened about what is ahead because of all this. It's just not fair. I am usually so conscientious about my health. What's a person to do???
Surely these bad health problems DON'T develop in MOST of the patients who have been prescribed it ???
OK, Now I am having a panic attack. Lately I've managed to get my anxiety under control, not letting things bother me, but now, I am scared to death from all these horror stories that have been posted here today! I guess now i understand the saying "Ignorance is bliss". i wish I hadn't asked, I think I was better off not knowing... : (
I'm so sorry. Believe that you will be one of the lucky ones. Just do us who have suffered, a favor, and tell others to ask for something else to ease their worries. It's taught me to not always trust a doctor and always investigate before taking something again.
Surely there are also people who have had positive experiences from this medication. I am truly sorry to all of you who have had these horrible experiences.
G mc; you are right with as much as these medications are prescribed you should not worry and more so from a doctor that is a specialist in the condition that you were treated. There are always nightmares stories about what can happen but of the millions of prescriptions that are dispensed with no ill effects. As I was saying you have to with anything weigh the risk vs the treatment such as Cipro in the same family is used so much for people to take at the first sign of diarrhea in a foreign country. And the one antibiotic that is effective for exposure to AMTHRAX POISENING it is still a case by case and a doctor that really knows what they are doing. To date I have not received any updates through the board of pharmacy saying much different than the original.
please relax I believe a big part of all these answers are people well more than likely answer if something negative had happened and others don't say much at all and also that with the millions of prescriptions still dispensed with these medication you are in fine shape. sadly with almost any medication otc and prescription there is no real way to find who might get the serious side effects. This same story can go with just about anything we take. Then you add interactions of other things be it food Vitamins something else some people may have been taking at the same time. I really feel you have nothing to worry about. Chuck1957 please don't worry and calm down this is the hard part about a medication that is so widely used but should be used by only the specialist that know what is going on and the chances of any serious problems with any medication. And at this point you are doing better than you have or were and if any doughs please call your physician Your friend Chuck. AND to all these poor people be it the medication or something else I hope all these studies that are going on well bring fast and speedy results to everyone's problems and hope it is a easy fix. My heart goes out to each and every one of you. God bless you all.
I wouldn't worry if I were you. I answered your question earlier because I thought you might already be experiencing a reaction and were feeling alone and unsure about what to expect. Most people can take a certain amount of poison and their bodies deal with it just fine. Everyone has a threshold, and not everyone has a bomb go off the first time they use this medication. Every person will have this reaction, however, if they are subjected to a high enough dose for a long enough period of time. With everyone being individuals, it is hard to predict who will make it through a course without noticing any problems, and who will be maimed for life. Since the damage is cumulative, if you've never used these drugs before, you will likely be alright.
Anachronist; and G mc, In all my years as a licensed certified Pharmacy Technician C. Pht; I try and always have tried to keep a open mind with my customers and many were like friends it just about killed me when I got hurt. And it was off the job, I was helping move 4 cars out of someone's back yard and was between a huge truck and the car we were pulling down the driveway broke loose and I got stuck between the cars and crushed one leg and almost got both you could not even see my left leg between the bumpers of the car it was so squished and spread out. I was in almost a 3/4 body cast for 5 months or close. I thank God my head was down there checking the rope a second before. I worked 3 to 4 years longer and just could not take the pain and swelling anymore I know I am a very lucky man even if I have to walk with a cane now. But the last 2 years have been pure hell.
I have been fighting cancer and still am, Then because I went back to work after the leg, I screwed my disability up after 45 years of working. But learned a lot during this time I have kept up with pharmacy. But anyway I talked to a few pharmacist I know, And also have not gotten any urgent message's about this class of medication. I am going to call the board of pharmacy today and see if there is some more info. About this. I was not a regular Technician I took special classes in science and focused on drugs and what different things meant even the Pharmacist would come to me and ask questions about many medications. I believe many unexplained things in drugs many times there is a reason. And all of these antibiotic's we really do have to keep our own eyes open and check them out. A lot of doctors out there should not even be.. Many all they know about a drug is what the salesman tell them but I never dough a patient it is there body they know it better than anyone. There are a lot of things that can be possible we all have our own chemical system going through our bodies and the drug is a different chemical all together. And just because a drug does something to someone does not mean it is going to happen to everyone. But many drug studies are done on a small scale be it with people or mice, The real trials are when they are approved for Prescription use and millions of people are taking these medications and if enough people don't turn in side effects etc. to the Dea or food and drug administration you may never know of some of the serious side effects that are going on. But the medication's we are all talking about have very patient effects and really are for bad Infections not for a minor skin problem or UTI, And do have different risk then the average medication. With luck and more studies they may find a good answer for all of these different side effects and it could be very simple. But for many these drugs have been life savers. But bottom line is we are all different and for the amount of this class of medication dispensed and used thank God this does not happen to everyone, Just like any other medication be it a prescription or an over the counter medication we all react differently to these because we are all different. And just like one heart pill you give it to the wrong person it can kill them, But the right person it could give them many more years of life. Or you can never tell what is going to happen when you get an interaction with another drug or a type of natural medication so anything could cause problems with any given group of people. Just for all of these with all these sad stories of what has happened to them. I hope they do some more research and find out why these things happened and be able to correct it and give them back there quality of life that they had before taking this medication. I hope this is able to be followed and people understand some of what I am saying and it makes some since. Just don't give up hope the answer could be just around the corner. But we sure don't need to scare the heck out of people because as with any prescription there are a lot of problems with them as far as how each person well react to the medicine. Just because a Doctor say's here take this and you well be better, We also have to look out for ourselves too. all of you have a good day and I WISH YOU NOTHIG BUT THE BEST. CHUCK1957
I took levaquin for a sinus infection. I even read about the side effects online prior to taking levaquin. It was only an antibiotic, what was there to concerned about? My thought was, I am middle-aged and healthy those side effects only happen to older or unhealthy people? During the duration of time I was taking levaquin, I only experienced mild side effects. I experienced very slight nausea,1 episode of dizziness, and some moderate foot pain that only in the morning. None of the side effects were very concerning and nothing was extreme. After I finished taking the levaquin the side effects eventually subsided. Four months later I was devastated with side effects that are disabling. It took several weeks of research to connect the dots, and realize my symptoms were related. Every symptom I am experiencing is related to my taking levaquin and is practically text book, according to the fda and trusted resources, i.e. Mayo clinic.
The disconnect with levauin side effects are occurring because there is a dormant phase where you "seem" ok, then the side effects appear several months later and blind-side you! I took levaquin in October 2015, my symptoms appeared in February 2016. My debilitating side effects are way too lengthy to cover here. levaquin side effects are progressive and only worsen as time goes on.
My husband took two days of it and then couldn't walk. His legs were put in casts and a wheel chair and he still cannot walk well. It has been a year and he still suffers from the pain. I have told everyone to not take this drug. A healthy 40 year old died two days later from taking it. His wife is working to get it off the market with the FDA. It is dangerous and not worth the gamble. Will you be the one? No one knows. The first person sued for 5 million dollars and won. They then put warnings on the package and no one can sue. It is so sad to read the people who are suffering right now. Just read their stories. I will work to get it off the market before someone else dies. Perfectly healthy people are now crippled. He just had a sinus infection...
Yes, I didn't end up in a wheelchair until a few months after taking the drug. I didn't feel quite right when I was on the antibiotics, but the crippling effects continued to escalate long after finishing the medication.
My husbands first symptom was tingling in the legs and just didn't feel right. This was before he woke up and couldn't walk...
I had diverticulitis. Was given cipro and flagyl. Did not take flagyl because i was unfamiliar with it. I did take the cipro because i had taken it 10 years prior with no side effects. Well i have been suffering from day 8 of the prescription ever since. Almost 2 years. Body wide tendonosis leaving me unable to work. Cipro and levaquin are from the same source.
Don't risk taking this drug for any reason. Not worth the years of chronic pain. One side effect is death. I had a delayed reaction to this drug that has now destroyed tendons, joints, gastrointestinal system, central nervous system... you name it. It has totally destroyed my life. I'm now housebound with damaged eyesight and hearing. I am literally wasting away. This drug should be off the market.
Don't be fooled if you don't have an immediate reaction. It can be a time-bomb drug.
I was admitted to hospital after an undetected kidney infection got into my blood. Almost died was put on levaquin. I now have pain in both wrists, elbows, & my knee. The pain is constant and I am weak from it. How long does this last?
Forever at least 14 years in my case
Why are some comments in pending. This is bad for your sight
Your Levaquin link to side effects is seriously outdated. Please see FDA black box warnings and update.
morning G mc; Really all I can say is looking at most the stuff you are looking at if you look close all of these things are very rare and things that have happened right away. But I know I filled a lot or prescriptions for this combination more than I can even remember and never seen anyone have any problems. Try not to worry but if anything feels out after you have taken it call your doctor but very doughtful from my experience hang in there hope you feel better.
You know, Chuck, I felt perfectly fine when I took it. I had a very serious infection, so taking levaquin wasn't an option. I was in so much pain for about 2 months. I'm starting to get better, just very fatigued. But that will pass. I wasn't worried about levaquin till I started reading patient reviews that told some real scare stories about what happened to them. But, for me, so far, so good. It was a strong antibiotic to treat a serious infection.
I truly appreciate your input on this. I value your opinion considering your career in the medical field.
I hope you are having a good day, and feeling better. "G"
G; That was very sweet of you and I do understand. But at times we have very little choice when something is the one thing that well do the job. This is where having a good doctor and a Pharmacist you deal with regular etc. is so important. So they get to working like a team. thanks again for being so sweet I needed that today. hugs Chuck
Philay: I also have diverticulitis. In 5 years I've had 4 attracts. I cannot take Fluouroquinolones because I was poisoned by Levaquin in 2001 for bronchitis. I had/have tendonitis, tendenosis, peripheral neuropathy in my lower extremities. No cure for the above and it NOT RARE. For diverticulitis I'm treated with Flagyl and Bactrim and immediately go on total clear liquids for at least 7-10 days!! Good luck!!
Please check your FDA updates. And at anytime you can google Levaquin. Most Drs are not aware or simply do not care what a fluroquinolone drug can do. These are facts and studies. In your search you will find that even death is a result of these drugs. For some it comes quick, others have a better tolerance and it builds up in all your systems attaches to your DNA and destroys your life as you knew it. This drug has been around for decades and we are just now proving that we were the lab rats. The human body is amazing. It alerts you with pain, the sniffles, runny eyes, all th things that are annoying you are signals telling you something is wrong. Sure, all drugs have side effects. I am no Doctor, however no one knows my body as I do. Fluoroquinolones has destroyed my life. If this happens to make it to you and they actually publish this, and you have a Facebook page. Search any of these words. Levaquin, cipro, avelox , fluoroquinolones, or simply antibiotics. You will find groups where this is not so rare. I wish you the best.
In 2001 I took 5 tablets of Levaquin and suddenly I could not walk or crawl because of intense pain. I had tears in Achilles' tendons (fortunately they did not rupture). I was housebound for six months and then every step was torture. Tendons on my legs, feet and knees were brutal. Orthopedic dr. Gave me steroid injections which worsened things. Remember it is not rare and can and does affect many people many different ways. It is 15 years now and I never take one step pain free. I was hospitalized the first time I had diverticulitis in 2010. I would not take Levaquin, so the Flagyl and Bactrim worked fine. Beware and be careful. It is NOT RARE!!
I took 9 Fluoroquinolones for 9 days (1poison a day) for a suspected UTI infection that I didn't even end up having... and 3 years later ... I have 3-4 dozen serious adverse damages and misdiagnosis. Heart, liver, kidney damage - heart palpations, arythmia, Digenerative Disc Diaese, and lost almost 3 inches (within 1 1/2 after taking this FQ poison) in my height, lost my sleep, my hair falling out by the handful, pychotic nightmares... could tell if I was awake or sleeping... all in the 20 min. Total sleep I got each night for 2 years straight! numbness, developed sudden arthritis, Ostepema, partially paralyzed ... Couldn't stand or walk for more than 5-20 min. 24/7 non-stop excruitiating pain from head to toe, inside and outside.. There are dozens more... all this came out within with days up to 7 months after taking the 9th FQ pill.
Weren't you told that some people adverse reactions only come out after 7 months and some took 2-3 FQ treatments over 2-3 years and whamo suddendly they are hit and knocked off their feet ... never connecting the dots for for years... Even 10-20 years. FQs damage the Mitichondria, which we are still fighting the FDA on, but thank God, we managed to get another blackbox put on it 9 days ago May 12/16 ... That ALL FQs cannot be given any longer for colds, sinus infection, pink eye, UTIs, pre surgery for preventative bacterial infections... no more FQ for any minor bacterial infections and right on the FDA site it list a few more adverse reactions of still the dozens and dozens and dozens that have not been acknowledged still... Links to Mitochindria and DNA damage. Many have been misdiagnoised for ALS, Parkinson's, Alsymers, Fibromagyia, Lyme, cancer, and rare dieases too. We still have a long hard fight. Many believe these antibiotics need to be pulled off the market entirely... These are actually Chemotheraputic drugs! Yes! Even some fatal patients that survicec cancer many just ended up dying because of Cipro, levaquin and the dozens of Fluoroquinolones that are given out like candy.
There is so much more. Best thing is to educate yourself so you can make an informed decision if your health and life is worth losing for a simple bacterial cold or pink eye or a UTI. Now doctors will be able to say your infection was complicated... to cover there ass. There are many good doctors who know for years not to give FQs or any antibiotics unless your life depebded on it... But there are not too many good doctors like that or doctors who innocently gave FQs to there patients believing the big pharmascuetical monsters and the FDA, commissioner and her husband have millions of damages and deaths on their hands for sitting and hiding the scientific evidence of mitochondria damage. I hope this is published because this is the truth and the world needs to know in order to protect their loved ones lives. Thx
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