I’m on 40mg of fluoxetine daily (supposed to be 60mg but managing on 40) for anxiety and depression but struggle quite regularly with muscle spasms during the night so doctor has put me on 10mg daily of amitriptyline at night time to help stop the muscle spasms but as I said I struggle with anxiety and I’m worried about mixing both medications, has anyone else had this combination that could offer some advice please?
Amitriptyline - Has anyone taken amitriptyline with fluoxetine?
Question posted by Katieeeemann on 7 Jan 2021
Last updated on 10 January 2021
Answers
Silimus
7 Jan 2021
Its such a small dose of amitriptyline that it shouldn't cause any issues. The main concern would be serotonin syndrome, but you are on such a low dose of amitriptyline so they shouldnt intervene with the fluoxetine.
Hope this helps.
Silimus
7 Jan 2021
By the way. I take amitriptyline for muscle spasms too. I was on both of these together but recently changed from fluoxetine to citalopram. I recommend taking amitriptyline just before bed or 3 hours before sleep if you have sleep issues
Katieeeemann
7 Jan 2021
And you didn’t have no side affects/ reactions?
Silimus
7 Jan 2021
None at all, but if I take the amitriptyline too early it makes me really tired. I take it 2-3 hours before bed. No other symptoms. 10mg is a really low dose. Dont worry :)
Katieeeemann
7 Jan 2021
Thank you so much for your help, you have eased my mind! Really appreciate it
Silimus
10 Jan 2021
Anytime. Hope it all goes well. Happy new year
Related topics
depression, anxiety, muscle spasm, amitriptyline, fluoxetine, anxiety and stress, doctor, muscle
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