I am on amitriptyline for 9 months 10 mg. Wonderful drug for anxiety, depression, Interstitial Cystitis, and gerd disease!! However... it came with chronic consitpation working on getting on the right medication for that I have tried everything almost. So.. I noticed my worrying , anxiety, bladder pain and gerd has came back after 9 months of taking it. So I went up to 15 mg. for 7 weeks and has not get better. So.. I went up to 20mg. for 8 days and still... the same I have anxiety, depression, bladder pain, and gerd still and worse more then ever! Has my body gotten use to it or do I need to go up more ? Does anyone have this problem?