Started out taking 200mg Sertraline daily for anxiety/depression. Just recently got on 10mg Adderall and now 20mg for ADHD. Started noticing upset stomach and headache as well as my heart feels like it is beating very fast. Is this normal. Don’t feel like I should be taking these medications at the same time because I have read they are not to be taken together.
Adderall/Sertraline - currently taking together?
Question posted by 0692hh on 28 Sep 2021
Last updated on 2 July 2025 (4 weeks ago) by Tom_joolery
The information on this page reflects personal experiences shared by our community members. It is not reviewed for medical accuracy and should not replace professional medical advice.
Answers
Hi there,
First thing: what you're experiencing could be a sign of something very serious, but it likely is immediately resolvable.
I am on the tail end of the exact same thing you're experiencing and you should talk to your doctor immediately. I had the same dosing as you and it induced serotonin syndrome, which can be fatal (I don't mean to scare you but it is that serious). If possible and with your own/doctors judgement come off your Adderall immediately and see if your symptoms resolve. If you are experiencing the start now, they may worsen as serotonin builds up in your system if you keep your current dosage. (effectively you are experiencing the beginnings of a serotonin overdose)
My psychiatrist prescribed me sertraline while I was taking 20mg of Adderall twice daily. I took them together for about a year. Initially, I asked him about taking them together and he said it was safe. After the first few months he suggested I take the sertraline at a certain point in my day - for better affect with my personal side effects (I think fatigue was an issue but it was about two years ago and I don’t remember entirely). I just remember that I stopped taking them because I didn’t really need them anymore and I felt like they were causing drag in my energy. But your side effects sound concerning and everyone is different, so whether or not they are safe to take together you should talk to your doctor about weather you should continue to do so, as soon as you can.
I hope this helps!
Related topics
adderall, depression, headache, anxiety, nausea/vomiting, attention-deficit hyperactivity disorder (adhd), sertraline, heart, stomach
Further information
Similar questions
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.