ACE-Inhibitors - Angiotensin Converting Enzyme (ACE) Inhibitors, are a family of medicines used primarily for the treatment of hypertension (high blood pressure) and congestive heart failure. They can also be used for diabetic nephropathy (kidney problems) and after a heart attack if the heart muscle is not working very well.
ACE-Inhibitors work by suppressing the angiotensin-aldosterone system (via ACE) which prevents the formation of angiotensin II (powerful vasoconstrictor). This plays a major role in the regulation of blood pressure and reducing pre/after load on the heart which improves the ability to pump blood around the body for the patient.
It is a blood pressure medication. ACE stands for the way it works. It lowers the blood pressure by inhibiting the release of angiotensin converting enzyme. Thus ACE. This interferes with the conversion of angiotensin 1 to 2.
Angiotensin 2 increases blood volume and also increases the blood pressure.
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