What I'm wondering is if 150mg Of Vyvanse is too high or even a dangerous dose for someone who has been prescribed Adderall XR (Varying doses) for five years and seems to have built a concerning high tolerance to amphetamines. Thanks!
The maximum recommended dose of Vyvanse is 70mg/day.
Adderall and Vyvanse both contain amphetamines and work in a similar way to treat attention deficit hyperactive disorder (ADHD) in adults and children.
Adderall is a mixture of four different kinds of amphetamine salts (one of which is dextroamphetamine) while Vyvanse only contains one salt, called lisdexamfetamine, which only gets converted into dexamphetamine once it is in the body.
Studies have shown that Vyvanse is just as effective as Adderall, and side effects are similar. One advantage of Vyvanse is that it may be less likely to be abused; however, there is no generic form available so it is more costly than generic forms of Adderall. Risk of dependence (coming to rely on the drug) appears similar for both.
The recommended starting dose of Vyvanse 30 mg once daily in the morning in patients ages 6 and above. Dosage may be adjusted in increments of 10 mg or 20 mg at approximately weekly intervals up to maximum dose of 70 mg/day.
No, because Vyvanse is only 1/3 dextroamphetamine, it’s equivalent moreso to 50mg of Dexedrine IR at 150mg. Maximum Dexedrine dose is 60mg, so would not be surprised to see such a conversion depending on dose of Dexedrine or Adderall. Some only get 6 hours active life, some get 12, so 70mg as a recommendation is just a recommendation likely because they don’t produce a larger capsule.
It is true that the recommended dosage is no more than 70mg a day. It is also true however, that each person processes drugs differently and also have varying tolerances to medication. I am on 70mg/twice a day, and was on 60mg IR adderall for almost two years. This dosage is becoming more common with people who are switching to Vyvanse after being on Adderall for 12 months or more. Also, whoever was citing the FDA as a valid source, are you aware that just this past month they are being sued for tampering with a study on Marijuana's effects on PTSD? The study showed how promising THC is for Veterans with PTSD, and the FDA was not happy. Google "Arizona Cannabis study." This is but one example of why the FDA should be taken as a "guide" and not scripture of the medical world.
I currently take 60mg vyvanse in the morning and 30mg In the afternoon so that’s above 70mg total.
If you by mistake take two pills just make sure you eat something high in protein and fat and it will relax the anxiety and side effects. Avoid caffeine, high carbs, and sugar when you accidentally take too much.
I take a total of 90 because my tolerance has built up since 5th grade but I seriously don’t recommend unless you understand it by taking it for a good amount of time.
I was prescribed Vyvanse and Adderall (generic) at the same time. I took a 70 mg Vyvanse in the morning, and if needed, had the option to take a 20 mg of immediate release in the early afternoon.
Worked well. Many times, I didn’t need the second dose.
As already mentioned, amount of substance is not even 1/3.
I have 280 mg/day. That's four 70 capsules. Some 84 mg:s of amphetamine.
Psysically, everything has become better every time it's been raised. To have a chance of functioning cognitively - I'd need a whole lot more. I happen to have some ADHD. I happen to respond somewhat differently to CS compared to normal people.
Most of these responses are half answers or make no sense, the reason the recommended dose is 70mg is because this medication is meant to be used for ADHD and BED. IT IS ONLY EFFECTIVE on lower doses of the drug. If taken too high the person will experience intoxication, or a HIGH from the drug. These medications are controlled substances for a reason so that a medical professional can only administer or prescribe these drugs. So that they can watch the patient and weigh the risks and needs, it is also setup this way so that if Doctors are over prescribing or abusing the system someway with these narcotics they can be held accountable. Vyvanse is made specially so when in the body it will only work once it is orally taken and processed via. Blood cells and the liver.
But also after time people can build up a tolerance or the depending on body weight age and lifestyle these factors can play into the dosing and changing overtime. However even with all that it wouldn't make much difference of the range of dosing size and effectiveness of the drug. The strength of this amphetamine and it effectiveness in the body, The cap on recommended dosage is 70mg after that you may be getting into intoxication. For a person who never takes the drug there is no body tolerance to it therefore just by taking 60mg for a normal person may lead to some intoxication (or high). Taking 150mg is pushing the limits, because its double it can be dangerous, the drug is very potent, so 150mg is more then likely too much for somebody who never takes the stuff and may abuse it. Also effectiveness for helping a patient goes out the window. Furthermore, this drug comes in different strengths, 10, 20, 30, 50, I think there is even a 60 so if a Dr. wants to give a patient an off dose they will prescribe 2 capsules this is common for many drugs. Allowing / or only giving the patient only 1 capsule sounds nonsensical and unrealistic. So essentially because of what the drug was made for, taking more then 70 is usually ineffective because amphetamines for treatment of ADHD and BED are used in smaller does, to help patients focus and so on. SHORT ANSWER - taking 150mg for real treatment way to high and ineffective, taking this drug to get high would be still a lot.
It’s completely subjective and other countries actually have higher limits on stimulant dose. So much goes into dose including individual neurobiological variance from patient to patient, comorbidities, cardiovascular health, etc. As a rule of thumb, the lowest dose that controls the symptoms should be used, as all of these medications are taxing on the cardiovascular system. That said, there is no magic number and occasionally higher doses work better. This is do to genes and pharmacokinetics (PK) which in short means what the body does to the drug and pharmacodynamics (PD) or what the drug does to the body. In the case of(PK) for Vyvanse for instance , which is an inactive drug made active through CYPD6 metabolism; 7% of Caucasian people will be poor metabolizers and while they may need a smaller dose of an active medicine like adderall they would POSSIBLY need a larger dose of an inactive one like Vyvanse because they would convert it too slowly.
Conversely, a rapid metabolizer may be the opposite. While this is a good rule, as mentioned above, it’s not the only consideration. PD (what the drug does to the body) also plays a major role in the individual dose because every individual will have different issues with how the drug impacts their heart, lungs, brain, and as mentioned above, different comorbidities with these organs that could limit dose or medication selection.
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