I am on 112.5 mg of generic Effexor for 3 weeks now and so far things have been going up and down at this dose. Basically, one day will be very high anxiety and the next will be depression and on another day it will be a mix of the two or one or the other acting up and fading through out the day. Anyone have a similar experience and if so did it get better. Also, psychiatric doc wanted me to up to 150 mg after 2 weeks, but I'm always hesitant about upping dose due to potential for increase of side effects. I appreciate any help you guys can give. Thanks.